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替罗非班对急性心肌梗死患者PCI术后C反应蛋白的影响及疗效

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摘要 目的:探讨盐酸替罗非班对急性心肌梗死患者冠状动脉介入治疗(PCI)术后对C反应蛋白(CRP)、左心室射血分数(LVEF)、心脏不良事件(MACE)发生率及出血事件的影响。方法:将急性心肌梗死患者PCI术后随机分为替罗非班组130例和对照组130例,测定术前及术后CRP,术后1月左心室射血分数、MACE事件及出血事件。结果:与对照组相比替罗非班组PCI术后CRP水平明显降低(P<0.05);左心室射血分数较高(P<0.05);MACE事件发生较少(P<0.05);未增加出血事件(P>0.05)。结论:盐酸替罗非班对急性心肌梗死患者在PCI术后能够发挥抗炎作用,明显改善患者预后,临床使用安全。
作者 伊文
出处 《北方药学》 2013年第5期20-21,共2页 Journal of North Pharmacy
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参考文献6

  • 1Napodano M,Ramondo A,Tarantini G,et al.Predictors and time-related impact of distal embo-Lization during primary an- gioplasty[J].Eur Heart J, 2009,30:305-314. 被引量:1
  • 2Okamura A,Ito H,Iwakura K,et al.Clinical implications of distal embolization during coronary interventional procedures in patients with acute myocardial infarction:quantitative study with Doppler guidewire[J].JACC Cardiovasc Interv, 2008,1:268-276. 被引量:1
  • 3陈彦霞,陈春红,尹博英,胥磊.择期PCI对急性心肌梗死患者心功能的影响[J].中国老年学杂志,2010,30(20):2922-2924. 被引量:11
  • 4Morrow DA, Lemos JA, Sabatine MS, et al.Clinical relevance of C-reactive protein during follow-up of patients with acute coro- nary syndrome in the aggrastat-to-zocor trial [J].Circulation, 2006, 114:281-288. 被引量:1
  • 5Azar RR,Badaoui G,Sarkis A, et al.Effect of high bolus dose tirofiban on the inflammatory re-sponse following percutaneous coronary intervention[J].Clin Cardiol, 2010,33:E14-E 19. 被引量:1
  • 6陈文,张鸿举,王相智,王又平.冠状动脉内注射替罗非班治疗急性ST段抬高型心肌梗死的疗效和预后评价[J].徐州医学院学报,2010,30(12):861-863. 被引量:5

二级参考文献19

  • 1杨新春,张大鹏,王乐丰,徐立,葛永贵,王红石,李惟铭,倪祝华,夏昆,连勇,薛永利,马利祥.冠状动脉内应用国产替罗非班对急性ST段抬高心肌梗死急诊介入治疗后心肌灌注和临床预后的影响[J].中华心血管病杂志,2007,35(6):517-522. 被引量:74
  • 2Levy WC,Cerqueia MD,Weaver WD,et al.Early patency of the infarct-related artery after myocardial infarction preserves diastolic filling[J].Am J Cardiol,2001;87(8):955-8. 被引量:1
  • 3Hara Y,Hamada M,Shigematsu Y,et al.Effect of patency from coronary angioplasty during acute myocardial infarction on left ventricular remodeling and levels of natriuretic peptides later[J].Am J Cardiol,2001;88(6):683-5. 被引量:1
  • 4Kanamasa K,Ishikawa K,Ogawa I,et al.Prevention of left ventricular remodeling by percutanous transluminal coronary angioplasty performed 24 hours after the onset of acute myocardial infarction[J].J Thromb Thrombolysis,2000;9(1):47-51. 被引量:1
  • 5Yamagishi H,Akioka K,Hirata K,et al.Long-term outcome of primary percutaneous transluminal coronary angioplasty for low-risk acute myocardial infarction in patients older than 80 years:a single-center,open,randomized trial[J].Am Heart J,2002;143(3):497-505. 被引量:1
  • 6Abbate A,Biondi-zoccai GG,Bussani R,et al.High-risk clinical feature predict increased post-infarction myocardial apoptosis and the benefits as a result of an open infarct-related artery[J].Eur J Clin Invest,2003;33(8):662-8. 被引量:1
  • 7The TIMI Study Group.The thrombolysis in myocardial infarction (TIMI) trial;phase I findings[J].N Engl J Med,1985;312(14):932-6. 被引量:1
  • 8Blaufarb IS,Sonnenblick EH.The rennin-angiotensin system in left ventricular remodeling[J].Am J Cardiol,1996;77(13):8-16. 被引量:1
  • 9Marino P,Zanolla L,Zardin P.Effect of streptokinase on left ventricular remodeling and function after myocardial infarction:the GISSI trial[J].J Am Coll Cardiol,1989;14(5):1149-58. 被引量:1
  • 10Wiggers H,Nielsen SS,Holdgaard P,et al.Adaptation of nonrevascularized human hibernating and chronically stunned myocardium to long-term chronic myocardial ischemia[J].Am J Cardiol,2006;98(12):1574-80. 被引量:1

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