摘要
目的探讨曲美他嗪联合地高辛治疗房颤伴心力衰竭的疗效。方法选择房颤合并心力衰竭的患者作为研究对象,随机分为给予曲美他嗪联合地高辛治疗的观察组和常规治疗的对照组,观察治疗效果、检测心脏彩超指标及外周血中BNP、EP1含量。结果观察组总有效率为94.64%,疗效明显好于对照组(80.00%);E峰(72.35±7.39)cm/s、E/A值(1.386±0.154)、LVEF(65.38%±7.03%)、LVEDD[(54.39±5.42)mm]、BNP[(173.86±19.47)ng/L],EP1[(2.38±0.31)fmol/ml]均明显低于对照组。结论曲美他嗪和地高辛能够提高房颤伴心力衰竭患者的治疗有效率,对改善心室功能,具有积极的治疗意义。
Objective To study the effects of trimetazidine and digoxin on atrial fibrillation combined heart failure. Methods Patients with AF and heart failure were collected and randomly divided into observation group given trimetazidine and digoxin and control group given routine treatment. Then the curative effect, cardiac ultrasound index and BNP, EP1 content were observed. Results Total effective rate 93.33% of observation group was obviously better than control group ; E peak （72.35 ± 7.39 ） era/s, E/A （ 1. 386 ± 0. 154 ）, LVEF （ 65.38 ±7.03 ） %, LVEDD （ 54.39 ± 5.42 ） mm, BNP （ 173.86 ± 19.47 ） ng/L and EPI （2.38 ± 0.31 ） fmol/ml were significantly lower than those of control group. Conclusion Trimetazidine and digoxin can improve treatment efficiency,improve ventricular function they had positive therapeutic significance.
出处
《中华全科医学》
2013年第7期1005-1006,共2页
Chinese Journal of General Practice
基金
国家自然科学基金(81170220)
关键词
心房颤动
心力衰竭
心室功能
Atrial fibrillation
Heart failure
Ventricular function
