摘要
目的:了解鼻咽癌患者放疗后的不良反应及影响因素。方法:对2011年8月至12月在湖南省郴州市第一人民医院南院鼻咽癌中心住院的96例鼻咽癌患者进行调查。结果:96例患者中97.9%口腔干燥、72.9%厌食、70.8%吞咽困难、66.7%味觉改变、52.1%乏力、45.8%放射性皮炎、41.7%咽炎、20.8%张口困难,饮酒史可加重鼻咽癌患者放疗后口腔干燥的程度,女性鼻咽癌患者在放疗后易出现乏力,体质指数不同时,鼻咽癌放疗患者乏力程度有差异(P均<0.05)。结论:口腔干燥是鼻咽癌患者放疗后的最常见不良反应,营养状况是鼻咽癌放疗不良反应发生的重要影响因素,应对患者进行早期系统的营养干预。
Objective：To investigate the side effects of radiotherapy for nasopharyngeal cancer（NPC） and its influencing factors. Methods ：All 96 NPC patients received radiotherapy were surveyed by trained interviewers with self - constructed questionnaires. Results： The incidences of xerostomia, apocalipsis, dysphagia, dysgeusia, fatigue, skin reaction,pharyngitis/laryngitis were 97. 9%, 72.9%, 70.8% , 66.7% , 52. I%, 45.8%, 41.7% respectively. Drinking histories may increase the incidences of xerostomia after radiotherapy （ P 〈 0.05 ）. C, ende and body mass index were correlated with fatigue. Conclusion： Xerostomia is one of the most common side effects of radiation therapy. The nutritional status is one of the factors influencing of adverse reaction of radiation therapy. It is necessary to conduct early nutrition intervention in NPC patients.
出处
《现代肿瘤医学》
CAS
2013年第5期1013-1014,共2页
Journal of Modern Oncology
基金
郴州市第一人民医院科研项目(编号:N2010-100)
关键词
鼻咽癌
放疗
不良反应
nasopharyngeal carcinoma
radiotherapy
adverse reaction
