摘要
目的探讨原发性子宫颈恶性黑色素瘤的临床表现、病理特征、诊治方法及预后。方法回顾性分析2例经手术及病理证实的原发性宫颈恶性黑色素瘤患者的临床诊治及病理资料。结果2例患者均行根治性手术，免疫组化均提示HMB45及S-100阳性。术后分别给予Avastin抑制肿瘤新生血管生成治疗1次及3次，并分别随访9个月及10个月均无复发症状。结论HMB45及S-100对诊断恶性黑色素瘤有意义，手术治疗联合辅助治疗可改善其预后。
Objective To investigate the clinical and pathological characteristics of primary cervical malignant melanoma as well as its diagnosis, treatment and prognosis. Methods A retrospective study was conducted to analyze the clinical diagnosis, treatment and pathological documents of two primary cervical malignant melanoma cases confirmed by surgery and pathology. Results Both of two patients received radical surgery and the immunohistological results were positive for HMB45 and S-100. After surgery, one patient was treated with Avastin for angiogenesis inhibition for once and followed up for 9 months. The other was given three times and followed up for 10 months. No recurrence was observed in both cases. Conclusion HMB45 and S-100 are useful in diagnosis of primary cervical malignant melanoma. Surgical treatment combined with adjuvant therapy can improve prognosis.
出处
《中国妇幼健康研究》
2013年第2期276-277,共2页
Chinese Journal of Woman and Child Health Research
