摘要
目的:验证临床药师对普外科Ⅰ类切口手术预防性应用抗菌药物干预的效果。方法:对2010年9—11月(干预前)广西医科大学第一附属医院出院的106例普外科Ⅰ类切口手术患者和2011年9—11月(干预后)出院的107例普外科Ⅰ类切口手术患者预防性应用抗菌药物情况进行对比分析。结果:临床药师通过干预,抗菌药物预防性使用率由85.85%(91/106)下降为47.66%(51/106)(P<0.01);抗菌药物使用合理率由66.04%(70/106)上升为78.50%(84/106)(P<0.05);围术期不合理应用抗菌药物的表现形式均有不同程度改善;人均抗菌药物费用由313.17元下降为233.52元(P<0.01)。结论:临床药师实施合理用药干预,对促进医院安全、有效、经济地使用抗菌药物起到了积极作用。
OBJECTIVE：To verify the outcome of clinical pharmacists＇ intervention on prophylactic use of antibiotics for patients undergoing type I incision surgery in general surgery. METHODS： The prophylactic use of antibiotics in patients undergoing type I incision surgery discharged from the First Affiliated Hospital of Guangxi Medical University during Sept.-Nov. period of 2010（ before intervention, n = 106 cases）or during Sep.-Nov. period of 2010 （after intervention, n = 107 cases） was analyzed contrastively. RESULTS： Through clinical pharmacist＇ s intervention, the rate of prophylactic use of antibiotics decreased from （ 85.85% 91/106） to 47.66% （ 51/106 ） （ P 〈 0.01 ） ;the rate of rational use of antibiotics increased from 66.04% （70/106）to 78.50% （84/106） （P 〈 0.05 ） ;the manifestation patterns of perioperative non-rational use of antibiotics had improvement of varying degrees, and the average cost of antibiotics declined from 313.17 Yuan to 233.52 Yuan after intervention compared with before intervention （ P 〈 0. 01 ）. CONCLUSION ： Clinical pharmacists＇ intervention on rational use of drugs plays a positive role in promoting safe, effective and economical use of antibiotics.
出处
《中国医院用药评价与分析》
2013年第4期356-358,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
临床药师
干预
围术期
抗菌药物
Clinical pharmacist
Intervention
Perioperative period
Antibiotics
