摘要
目的:探讨精液中白细胞对精液各主要参数的影响。方法:回顾性分析216例男性不育患者的精液质量,根据WHO推荐的方法进行精液常规及精子形态学分析,利用联苯胺法进行白细胞检测,并将患者分为白细胞精子症(>1×106/mL)和非白细胞精子症(≤1×106/mL)两组。结果:与非白细胞精子症组(n=152)相比,白细胞精子症组(n=64)的精子密度明显降低[(38.36±23.16)×106/mL vs(47.14±19.70)×106/mL,P<0.01],活动率明显下降(43.50%±11.49%vs 48.17%±10.28%,P<0.01),a+b级精子比率明显下降(31.00%±10.64%vs 35.87%±10.66,P<0.01),正常形态精子百分率明显降低(10.75%±4.40%vs 12.31%±3.84%,P<0.05),而白细胞精子症组的精液液化异常发生率较非白细胞精子症组明显增高(14.06%vs 4.61%,P<0.05)。结论:白细胞精子症可导致精子密度、活动率及正常形态精子百分率的降低,并可引起精液液化异常发生率的增高。
Objectives： To study the influence of seminal leukocytes on sperm quality parameters. Methods： Semen sam- ples from 216 infertile men were evaluated retrospectively. Sperm concentration, motility, morphology and seminal leukocytes were analyzed according to the WHO criteria. All patients were divided into two groups as leukocytospermia（ 〉 1 ×106/mL） and non - leukocytospermia （ ≤1×106/mL）. Results： Compared with non - leukocytospermia group （ n = 152）, the sperm concentra- tion in leukocytospermia group（ n = 64） was much lower[ （38. 36 ± 23.16） ×106/mL vs. （47. 14 ± 19. 70） ×106/mL, P 〈 0.01 ）, the motility was much lower（43.50% ± 11.49% vs. 48. 17% ± 10.28%, P 〈 0.01 ）, the percentage of grade a ＋ b sperm was much lower （31.00%± 10. 64% vs. 35.87% ± 10. 66, P 〈0. 01 ）, and the percentage of normal morphology sperm was much lower （ 10. 75% ± 4.40% vs. 12. 31% ± 3. 84%, P 〈 0. 05）. Meanwhile, a significantly higher rate of abnormal se- men liquefaction was observed in leukocytospermia group than that in non - leukocytospermia group （ 14. 06% vs. 4. 61% ,P 〈 0. 05）. Conclusion： The results indicate that leukocytospermia has a significant negative effect on the sperm concentration, mo- tility, morphology and the semen liquefaction.
出处
《中国性科学》
2013年第5期3-6,共4页
Chinese Journal of Human Sexuality
