摘要
患者,女,55岁,于2006年12月因面部皮肤绛红、结膜充血入院。体检：体温36.8℃,血压140/103mmHg（1mmHg=0.133kPa）,脾肋缘下2.5cm。血常规：Hb 198g/L,WBC 13.38×10^9/L,PLT 468×10^9/L,
Five years ago,the patient was admitted into hospital because of red face and conjunctiva hyperemia. Physical examinalion {ound spleen subcostal 2.5 cm. A blood test showed Hb was 198 g/l., the WBC count was 13.38×10^9/L,and the PLT count was 468×10^9/L,Neutrophil alkaline phosphatase NAP integral 182. The results of a bone marrow analysis showed hyperplasia in the red lineage. The patient was diagnosed as having ploy cylhemia vera. In June 2011,this patient returned to the hospital because of right knee pain and gradually whole body bone pain,accompanied by chest tightness wheeze reentry. Physical examination found anemia,small petechiae,sternal tenderness,and splenomegaly. Blood lest showed Hb was 76 g/L,the WBC count was 29.93 ×10^9/L, and the PLT count was 24 ×10^9/L. A bone marrow examination revealed hyperplasia in the granulocytic and monocytic lineage, the original cells accounted for 60o/oo. The immune phenotype： original cells accounted for 87.72%, the cells expressed CD13, CD33, partly expressed CD117, CD34, HI.A-DR, CD1S, CD11b, CD64, CMPO.AK2V617F mutation （＋）. Therefore,the patient was diagnosed as having acnte myeloid leukemia （AMI. ML ）.
出处
《临床血液学杂志》
CAS
2013年第3期341-342,共2页
Journal of Clinical Hematology
