摘要
目的分析前列腺癌的MR扩散加权成像(DWI)及动态增强成像(DCE)表现,探讨DWI及DCE对前列腺癌的诊断价值。方法回顾性分析16例前列腺癌(Pca)及20例前列腺增生(BHP)的MR征象,全部患者行DWI及DCE检查,分析病例的DWI及ADC图像,测量Pca及BHP的ADC值。DCE共采集36次图像,分析Pca及BHP的时间-强度曲线变化规律。结果前列腺癌于DWI(b=800)图呈高信号,ADC图呈低信号;受侵犯的精囊膀胱及骨、淋巴结转移在DWI(b=800)也呈高信号,ADC呈低信号;前列腺癌的ADC值与前列腺增生的ADC比较,差异有统计学意义(P均<0.05)。癌灶的DCE表现为早期明显强化,峰值出现后强化度快速减低(快进快出),病灶范围显示直观、清晰;前列腺增生早期明显不均匀强化,持续时间较长(快进慢出)。结论 DWI、ADC值的量化指标及DEC图像表现的时间-强度曲线可提高前列腺癌诊断的正确率,并且可以直观显示病变范围及转移情况,对前列腺癌进行准确的分期评估。
Objective To discuss the diagnostic value of diffusion weighted imaging （DWI） and dynamic contrast-enhanced （DCE） in prostate cancer. Methods All patients included 16 cases of prostate cancer （Pca） and 20 cases of benign hyperplasia （BHP）. DWI and ADC map appearances were reviewed in all patients .ADC values of Pca and PBH tissues were measured and analysed statistically. Analyse DCE-MRI images are gathered for 36 times and its change rule of time intensity curve. Results All of the 16 Pca case showed markedly high-signal on DWI （b=800） and low-signal on ADC map. The invaded seminal vesicles and bladder, include bone and lymph node metastasis also appear similar signal intensity as Pca on DWI and ADC map. There were significant differences in the ADC values of Pca cases and BHP cases （P 〈 0.05）. Pca case showed obvious enhancement in early phase, and enhancement de- gree was rapid decreased after peak on DCE map. The extent of the lesions are simple and clear. BHP cases show obvious inhomogeneous enhancement in early phase and with long duration. Conclusion It has an important clinical value in diagnosing Pca with DWI and ADC values and change rule of time intensity curve in DCE, they could clearly demonstrate the area of Pca and metastasis tumor , which also can staging assessment of Pca.
出处
《中国现代医生》
2013年第15期114-116,共3页
China Modern Doctor
基金
广东省云浮市医学科学技术研究基金项目(2012B06)
关键词
前列腺癌
磁共振成像
扩散加权成像
动态增强磁共振成像
Prostate cancer
Magnetic resonance imaging
Diffusion-weighted imaging
Dynamic contrast-enhanced
