摘要
目的:检测CD146在子宫腺肌病中的表达情况,从而进一步研究子宫腺肌病发病中的参与因素。方法:用SP免疫组织化学方法检测CD146在30例AM在位内膜、异位内膜和30例正常子宫内膜的表达。结果:(1)AM异位内膜及在位内膜组织CD146的表达强度均高于对照组(均P<0.05),AM异位内膜高于在位内膜(P<0.05);(2)CD146在三种内膜的表达均为分泌期高于增生期,但在正常内膜两者的差别无显著性(P>0.05)。结论:CD146在三种子宫内膜中表达的不同变化参与了子宫腺肌病发生、发展的过程。
Objective：To detect the expression of CD146 in adenomyosis for further study the involvement of factors in the pathogenesis of adenomyosis. Methods： The expression of CD146 was detected by SP immunohistochemical method in eutopic endometrium and ectopic endometrium from 30 cases with AM and 30 cases of normal endometrium. Results： （1）The expression of CD146 in the ectopic and eutopic endometrium of adenomysis significant higher than that in control group（ P 〈0.05）. The expression of CD146 in ectopic endometrium was higher than that in eutopic endometrium. （2）The expression of CD146 in the three kinds of endometrial was higher in secretory phase than proliferative phase,but the difference in the normal endometrium was no significant（ P 〉0.05）. Conclusion：The different expression of CD146 in the three endometrial may involved in the development of adenomyosis.
出处
《长治医学院学报》
2013年第2期101-103,共3页
Journal of Changzhi Medical College
