摘要
为探讨血清前白蛋白（ＰＡＢ）和总胆汁酸（ＴＢＡ）在慢性肝病中的临床价值，分别检测慢性乙肝（轻度、中度、重度）、肝硬化（代偿期和失代偿期）患者及正常对照组的血清ＰＡＢ、ＴＢＡ及白蛋白（Ａ）、总胆红素（ＴＢＩＬ）水平，并进行分析。结果显示，各型慢性肝病患者血清ＰＡＢ均显著低于对照组（Ｐ＜０．０５或Ｐ＜０．０１），而血清ＴＢＡ则明显高于对照组（Ｐ＜０．０５或Ｐ＜０．０１）。轻、中度慢性乙型肝炎患者的血清ＰＡＢ、ＴＢＡ异常率均高于同组Ａ和ＴＢＩＬ的异常率（Ｐ＜０．０５）。提示联合检测血清ＰＡＢ和ＴＢＡ有助于发现肝脏合成及代谢功能的早期损害。
To investigate the clinical value of serum levels of PreAlb(PAB)and total bile acid(TBA)of patients with chronic liver disease,the levels of serum PAB and TBA of patients with chronic hepatitis B and liver cirrhosis were detecled and analyzed,the significance of their changes in different stages of chronic liver disease comparing with the changes of serum albumin(A)and total bilirubin(TBIL)in these patients.The result showed that the serum levels of PAB of these patients were lower,while the levels of TBA were higher significantly than that of healthy controls(P<0.05< or P<0.01)In the patients with early hepatitis B,the changes of serum PAB and TBA were obvious than that of A and TB IL.The results suggest that the serum levels of PAB and TBA can be important markers for predicting the early damage of liver function
出处
《山东医药》
CAS
北大核心
2000年第13期3-4,共2页
Shandong Medical Journal
关键词
慢性肝病
前白蛋白
总胆汁酸
血清诊断
Chronic liver disease
PreAlb
Total bile acid
Early dam age of liver function
