摘要
目的观察不同剂量舒芬太尼全麻诱导对老年患者血流动力学的影响。方法 120例全麻老年患者随机均分为6组。以咪达唑仑0.08mg/kg、丙泊酚1.0mg/kg、舒芬太尼0.2～0.7μg/kg、维库溴铵0.1mg/kg麻醉诱导,记录诱导前(T0)、气管插管前(T1)、气管插管即刻(T2)、气管插管后1min(T3)、3min(T4)、5min(T5)的SBP、DBP、HR的变化。结果Ⅲ组与Ⅳ组比较,各时点SBP、DBP、HR差异无统计学意义(P>0.05)。与T1时比较,Ⅰ、Ⅱ组在T2、T3、T4、T5时SBP、DBP明显增高、HR增快,(P<0.05)。与Ⅲ、Ⅳ组比较,Ⅰ、Ⅱ组在T2、T3、T4、T5时SBP、DBP明显增高、HR增快,高血压、心动过速的发生率高(P<0.05)。与Ⅲ、Ⅳ组比较,Ⅴ、Ⅵ组在T1、T2、T3、T4、T5时SBP、DBP明显降低、HR减慢,低血压、心动过缓的发生率高(P<0.05)。结论舒芬太尼0.4～0.5μg/kg适合老年患者的麻醉诱导。
Objective To determine the effect of different doses sufentanil on hemodynamics in elderly patients during endotracheal intubation. Methods One hundred and twenty patients aged 65 to 79 years old undergoing selective surgery were devided randomly into＇six groups with 20 cases each. The patients were induced with midazolam 0. 08 mg/kg, propofol mg/kg, sufentanil 0. 2μg/kg （ group Ⅰ ）, 0. 31.Lg/kg （ group Ⅱ ）, 0.4trg/kg （ group Ⅲ ）, 0. 5μg/kg （ group Ⅳ）, 0. 6μg/kg （ group Ⅴ ）, 0. 7μg/kg （group Ⅵ） and vecuronium 0. 1 mg/kg. The values of SBP, DBP and HR were recorded before anesthesia （TO）, be- fore iutubation （T1）, the moment of intubatinn （T2）, 1min （T3）, 3min （T4） and 5min （T5） after intubation. Results Com- pared with group Ⅲ ,SBP, DBP and HR were no significant differences at each time point in group IV （P 〉 0. 05 ）. The incidence of hypertension and tachycardia in groupⅠ and Ⅱwere higher at T2, T3, T4 and T5 than those in group Ⅲand Ⅳ （P 〈 0.05 ）. The incidence of hypotension and bradycardia in group Ⅴ and Ⅵwere higher at T1 ,T2, T3, T4 and T5 than those in group Ⅲ and Ⅳ （ P 〈 0. 05 ）. Conclusion The hemodynamic was more stable in elderly patients induced with sufentanil 0.4 - 0. 5 μg/kg.
出处
《四川医学》
CAS
2013年第3期363-365,共3页
Sichuan Medical Journal
关键词
舒芬太尼
气管插管
老年
血流动力学
sufentanil
endotracheal induction
elderly
hemodynamics
