摘要
目的:探讨颈椎间盘退变发病机制,寻求有效阻断病情发展及治疗方法。方法:查阅国内外有关颈椎间盘退变机制的研究文献,熟悉有关颈椎间盘退变的动物模型,综合分析国内外专家学者的观点,从现代医学及传统医学等方面总结颈椎间盘退变的发病机制。结果:现代医学认为颈椎间盘退变与颈椎间盘力学因素、营养减少、细胞凋亡、化学物质的刺激、细胞基质成分的变化、微血管以及伴随神经末梢的长入等有关;传统医学认为颈椎间盘退变多由于肝之气血不足,血不养筋,肝疏泄失常等引起。结论:中医中药对椎间盘退行性疾病有良好的疗效,深入研究颈椎间盘退变的发生机制,运用中医药可以早期阻断病情进一步发展。
Objective ： To investigate the causes of the occurrence and development of degenerative intervertebral disc to find the effective way to stopping the progression of the disease. Methods ： Summarize the etiology and pathogenesis of degenerative intervertebral disc from modem medicine and traditional medicine through related literatures, familiar with the animal model and comprehensive analysis of the points of experts and scholars. Results ：The modem medical science thinks degenerative intervertebral disc were connected with mechan- ical factors, nutrition reduce, apoptosis, chemical stimulation, cell matrix change, capillaries and nerve endings and so on. Traditional Chinese medicine believes that degenerative intervertebral disc caused by liver qi and blood deficiency and abnormal liver function. Conclusion ：Traditional Chinese medicine is effective in the treatment of degenerative intervertebral disc. Further study of the mechanism and using TCM can be earlier to block the further development of the disease.
出处
《中医学报》
CAS
2013年第5期747-749,共3页
Acta Chinese Medicine
基金
江苏省六大人才高峰项目(编号:2010-WS-071)
关键词
颈椎间盘退变
发病机制
力学因素
营养减少
细胞凋亡
degenerative intervertebral disc
pathogenesis
mechanical factors
nutrition reduce
apoptosis
