摘要
目的:探讨慢性心衰(CHF)患者血浆脑钠肽(BNP)检测的临床价值.方法:采用荧光免疫分析对101例CHF患者及45例健康对照者进行血浆BNP测定,同时以彩色多普勒超声心动仪测定CHF患者左心室舒张末期内径(LVEDD)、左心室射血分数(LVEF),并与血浆BNP水平作相关性分析,并对治疗心衰前后患者BNP水平作对比分析.结果:CHF组患者血浆BNP水平明显高于健康对照者(P<0.01);不同心功能级别之间BNP值差异有统计学意义;心衰患者血浆BNP水平与NYHA、LVEDD、LVEF有明显相关性.结论:BNP是评价CHF患者心室功能的灵敏指标,BNP的检测在慢性心衰的诊断及治疗中具有较高的临床价值.
Objective： To investigate the clinical value of detection of brain natriuretic peptide （BNP） in chronic heart failure （CHF） patients. Methods： The plasma BNP in 101 CHF patients and 45 healthy controls were measured by fluoroimmunoassay, meanwhile, the left ventricular end-diastolic dimension （LVEDD）, left ventricular ejection fraction （LVEF） of CHF patients were measured by Doppler ultrasound cardiograph, their correlation with plasma BNP levels were analyzed, and BNP levels before and after treatment were compared and analyzed. Results： plasma BNP levels in CHF patients were significantly higher than healthy controls （P〈0.01）, and the BNP values among different classes of heart function had statistical significance （P〈O.O1）. There were good correlation between BNP levels and NYHA, LVEF, LVESD in CHF patients （P〈0.01）. Conclusion： BNP is a sensitive index to evaluate the ventricular function of CHF patients, and the detection of BNP has a high clinical value in diagnosis and treatment of CHF.
出处
《内蒙古民族大学学报（自然科学版）》
2013年第1期94-96,共3页
Journal of Inner Mongolia Minzu University：Natural Sciences
关键词
脑钠肽
慢性心衰
诊断
Brain natriuretic peptide
Chronic heart failure
Diagnosis
