摘要
目的:观察针刺对肝硬化胃肠动力障碍的治疗作用。方法:将40例肝硬化胃肠动力障碍患者随机分为针刺组和吗丁啉组,每组20例。针刺组在常规治疗基础上每日电针足三里、三阴交、太冲30min;吗丁啉组在常规治疗基础上餐前30min口服吗丁啉,每次10mg,每日3次。两组均治疗2周。观察消化道症状评分和肝功能Child-Pugh评分的改变,并进行疗效评定。结果:针刺组消化道症状总有效率为85.0%(17/20),而吗丁啉组为70.0%(14/20)。针刺组腹胀、嗳气、呕吐的积分改善均优于吗丁啉组(均P<0.05)。针刺组治疗前肝功能Child-Pugh总分为8.40±0.22,治疗后下降至5.36±0.17,其中腹水、血清胆红素和白蛋白的评分均降低(均P<0.05),且下降幅度随消化道症状的改善有增大趋势,而吗丁啉组Child-Pugh评分较治疗前无明显变化。结论:针刺能有效减轻肝硬化患者的消化道症状,并改善肝功能,其对肝硬化胃肠动力障碍的疗效优于吗丁啉。
Objective To observe the therapeutic effect of acupuncture on gastrointestinal dysmotility in liver cirrhosis. Methods Forty cases of gastrointestinal dysmotility in liver cirrhosis were randomized into an acupuncture group and a motilium group, 20 cases in each one. In the acupuncture group, on the basis of the conventional treatment, electroacupuncture was applied at Zusanli （ST 36）, Sanyinjiao （SP 6） and Taiehong （LR 3） for 30 rain, once a day. In the motilium group, on the basis of the conventional treatment, motilium was taken orally 30 min before meals, 10 mg each time, three times a day. The treatment was required for 2 weeks in both groups. The changes in the digestive tract symptom score and liver function Child-Pugh score were observed and the efficacy was assessed. Results The total effective rate of digestive tract symptoms was 85.0% （17/20） in the acupuncture group and 70.0% （14/20） in the motilium group. The score improvements in abdominal distention, belching and vomiting in the acupuncture group were superior to those in the motilium group （all P〈0.05）. In the acupuncture group, the liver function Child-Pugh total score was 8.40-4-0.22 before treatment and reduced to 5.36±0.17 after treatment, in which the scores for ascites, serum bilirubin and albumin were all reduced （all P〈0.05） and the reducing range was increased in tendency with the improvements in digestive tract symptoms. In the motilium group, Child-Pugh score was not changed obviously as compared with that before treatment. Conclusion Acupuncture effectively alleviates digestive tract symptoms and improves liver function for the patients of liver cirrhosis, its efficacy on gastrointestinal dysmotility in liver cirrhosis is superior to motilium.
出处
《中国针灸》
CAS
CSCD
北大核心
2013年第5期389-393,共5页
Chinese Acupuncture & Moxibustion
基金
广州市医药卫生科技项目:20122A011020
关键词
针刺
肝硬化
胃肠动力障碍
临床研究
acupuncture
liver cirrhosis
gastrointestinal dysmotility
clinical research
