摘要
对关节内用药止痛进行比较。方法 :选X线及关节镜下诊断为Ⅱ、Ⅱ +期骨性关节炎患者术后随机注入 1mg吗啡、0 .5 %布比卡因 10ml、5mg地塞米松、透明质酸钠 2 5mg或 10ml生理盐水 ,在术后第 1、第 2、第3天及第 15天记录疼痛评分 (按Ventafridda所设计表 ) ,结果用 q检验。结果 :术后第 1天各组疼痛评分如下 :生理盐水 17.0 0± 1.0 5 ,布比卡因 3 .70± 1.42 ,地塞米松 2 .30± 1.16 ,透明质酸钠 1.70± 1.2 0 ,吗啡 1.6 0± 0 .70。结论 :吗啡、布比卡因、地塞米松、透明质酸钠均有止痛作用 ;而透明质酸钠对关节软骨具有保护作用 ,所以从远期效果看 ,透明质酸钠是关节镜术后最佳的止痛药物。
Objective: To assess the analgesic property of intra-articular drugs. Methods: Patients who were examined II, II+ periods of osteoarthritis according to X-ray and arthroscopy were randomized injected 1mg of morphine, 10ml of 0.5% bupivacaine, 5mg of dexamethasone, 25mg of hyaluronic acid or 0.9% saline. The pain evaluation was recorded after first day, second day, third day and fifteenth day of post-arthroscopy according to ventafridda table. The results were analyzed with Newman-keuls way. Results: The first day of postarthroscopy each group pain evaluation as follows: Saline group: 17.00±1.05; Bupivacaine group: 3.70±1.42; Dexamethasone:2.30±1.16; HA: 1.70±1.20; Morphine: 1.60±10.70. Conclusions: The time of analgesic of Morphine, Dexamethasone, HA is longer than bupivacaine. The long-term effect intra-articular hyaluronic acid is beneficial. There is protective function on cartilago articularis.
出处
《中国内镜杂志》
CSCD
2000年第4期1-2,共2页
China Journal of Endoscopy
