摘要
幽门螺杆菌(Hp)是一种古老细菌,但是人们直到近年才发现并确定其与多种胃肠道疾病相关,如胃炎、消化性溃疡、胃癌等;在对Hp的科研创新中经历了许多的成功与挫折,如Hp的发现过程中的科研创新、思维变化;通过从临床流行病学到基础研究揭示胃癌与幽门螺杆菌的关系;Hp的治疗中所涉及的伦理,治疗策略问题;Hp在人类迁移的研究过程的意义,以及疫苗的研究过程中所面临的挑战与机遇等。本文通过回顾Hp的研究过程,简单揭示幽门螺杆菌科研过程中的科研思维变化。
Helicobacter pylori (Hp) ,an ancient bacterium, was found recently, and closely implicated in several gastrointes- tinal diseases,such as chronic gastritis, peptic ulcer, gastric cancer. In the course of studies to Helicobacter pylori, there are lots of successes and failures, such as the vicissitudes of thoughts and research innovation in the course of the discovery of Helicobacter pylori, revealing the relationship with gastric cancer through from clinical epidemio|ogic characters to basic studies, the ethic problems and therapy strategies on eradicating Hp, demonstrating human being migration through interdiscipline studies and the challenge on studies of vaccine of Helicobacter pylori. Through retrospecting these studies, we simple reveal the change of thoughts in scientific innovation and researches.
出处
《医学与哲学(B)》
2013年第4期89-91,共3页
Medicine & Philosophy(B)
关键词
幽门螺杆菌
科研创新
胃癌
疫苗
Helicobacter pylori, scientific innovation, gastric cancer, vaccine