摘要
目的 :探讨高原地区分别单独应用米非司酮、左炔诺孕酮及联合用药的紧急避孕效果 ;方法 :将避孕失败或无保护性生活后 72小时内就诊的 782例健康妇女分为 4组。Ⅰ组 2 1 2例 ,口服米非司酮 2 5mg,1 2小时后重复一次 ;Ⅱ组 2 0 5例 ,口服左炔诺孕酮 0 .75mg ,1 2小时后重复一次 ;Ⅲ组 1 82例 ,口服米非司酮 2 5mg一次 ;Ⅳ组 1 83例 ,口服米非司酮 2 5mg及左炔诺酮 0 .75mg;结果 :Ⅰ组、Ⅱ组均无方法失败而妊娠者 ,Ⅲ组、Ⅳ组各有 2例方法失败而妊娠者 ;避孕效率 4组依次为 1 0 0 % ,1 0 0 % ,84.3 % ,84.5 %。服药后月经影响小 ,副反应发生率低 ;结论 :单独服用米非司酮、左炔诺孕酮两次服法均可作为高原地区性生活后 72小时内有效紧急避孕方法。米非司酮与左炔诺孕酮合用 ,未显示出协同作用。
Objective:To study effects of mifepristone and Levonorgestrel for emergency contraception. Methods :782 healthy wemen,who have unprotected intercourse with in 72 hours,were divided into four groups.In group 1,25mg mifepristone was taken twice with 12 hours apart.In group 2,0.75mg LNG was taken twice with 12 hours apart.In group 3,single dose of 25mg was taken.In group 4,25mg mifepristone was taken with 0.75mg LNG.Contraceptive efficacy was calculated.Results:Group 1 and 2 did not occure prognancies.The preventing contraceptive efficacy rate was 100%.There were 2 prognancies occured respectively in group 3 and 4.The contraceptive effecacy rate was 98.9% in each group.The incidence of various side effects was less,but only dose of mifepristoin or LNG was better on emergency contraception than mixied them.Conclusion:Use of LNG and mifepristone for emergency contraception is effective and safe at high altitude.
出处
《高原医学杂志》
CAS
2000年第3期18-21,共4页
Journal of High Altitude Medicine
关键词
米非司酮
左炔诺孕酮
避孕
高原
High altitude
Contraception
Levonorgestrel
Mifepristone
