摘要
目的探讨老年胫腓骨开放性骨折术后并发感染的临床特点以及致病菌耐药性。方法对143例发生术后感染的老年胫腓骨开放性骨折患者进行感染因素、致病菌及耐药性分析。结果骨折固定方式不当、切口闭合不当明显高于其他导致感染的因素,差异有统计学意义(P<0.05);革兰阴性杆菌主要以大肠埃希菌、铜绿假单胞菌、褪色沙雷菌为主;革兰阳性球菌中耐甲氧西林凝固酶阴性葡萄球菌以及耐甲氧西林金黄色葡萄球菌的株数为6株以及11株,万古霉素和亚胺培南对其具有良好的抗菌效果。结论开放性胫腓骨骨折术术后患者感染主要是以革兰阴性菌为主,头孢哌酮/舒巴坦、亚胺培南、美罗培南对其具有良好的临床疗效。
Objective To investigate the clinical characteristics of the elderly tibia and fibula open fractures postoperative infection and pathogen resistance.Methods 143 patients admitted to our hospital elderly tibia and fibula open fractures in patients with a postoperative infection infection factors and pathogenic bacteria and drug resistance analysis.Results fracture fixation improper the incision closed improper significantly higher than the other factors that lead to infection(P<0.05).Gram-negative bacteria escherichia coli,Pseudomonas aeruginosa,main fade marcescens.Gram the number of trees for six and 11-positive cocci,methicillin-resistant coagulase-negative staphylococci and methicillin-resistant Staphylococcus aureus,vancomycin and imipenem has good antibacterial effect.Conclusion open tibia and fibula fractures in patients with postoperative infection in Gram-negative bacteria,cefoperazone/sulbactam,imipenem,meropenem have good clinical efficacy.
出处
《重庆医学》
CAS
CSCD
北大核心
2013年第11期1221-1223,共3页
Chongqing medicine
关键词
感染
胫腓骨开放性骨折术
病原菌
infection
open fracture of the tibia and fibula surgery
pathogens
