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急性缺血性脑卒中的静脉溶栓治疗 被引量:7

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摘要 急性缺血性脑卒中发病3h以内重组组织型纤溶酶原激活剂(recombimnttissueplasminogenactiva-to,rt-PA)的静脉溶栓治疗仍然是至今惟一被美国食品和药物管理局(FDA)批准用于急性缺血性脑卒中的药物治疗方法。虽然急性缺血性脑卒中治疗的基础理论研究已取得了很大的进步,针对缺血性脑损伤的不同机制,许多药物在动物试验获得了良好的疗效,如:兴奋性氨基酸受体拮抗剂、钙通道拮抗剂、自由基清除剂、白细胞粘附抑制剂、低分子肝素抗凝治疗等;但所有这些治疗方法均没有被严格的临床试验证实有明显的疗效或其疗效十分有限。
出处 《内科急危重症杂志》 2013年第2期76-78,共3页 Journal of Critical Care In Internal Medicine
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