摘要
目的探讨产褥感染患者产妇多项血清中相关细胞因子水平变化规律。方法选取39例产褥感染产妇为观察组,同期39例未发生感染的正常产妇为对照组,对2组产妇产后1、3及5 d的血清C-反应蛋白(CPR)、降钙素原(PCT)、白细胞介素-6(IL-6)、抗凝血酶原Ⅲ的活性(AT-Ⅲ:A)水平及抗氧化能力指标进行比较。结果观察组产后1、3及5 d的血清CRP、PCT、IL-6高于对照组;AT-Ⅲ:A水平观察组为(70.18±3.29)%、(63.41±3.06)%、(67.42±3.17)%,均低于对照组;SOD为(72.41±5.20)、(70.06±5.09)、(71.93±5.15)nU/ml,TAC为(7.26±0.98)、(7.03±0.96)、(7.59±1.04)kU/L,均低于对照组;MDA分别为(3.39±0.35)、(3.78±0.39)、(3.50±0.33)nmol/ml,MPO分别为(2.78±0.26)、(3.12±0.35)、(2.87±0.29)mg/L,均高于对照组;在不同类型产褥感染患者中,盆腔腹膜炎患者的变化幅度>其他患者,差异均有统计学意义(P<0.05)。结论产褥感染产妇多项血清因子水平的变化与疾病严重程度相关。
Objective To study the variation of multiple serum factors of lying - in women with puerperal infection. Methods 39 lying - in women with puerperal infection in our hospital were selected as observation group, and 39 lying - in women without puerperal infec-tion at the same time were selected as control group, then the serum CRP, PCT, IL-6, AT-Ⅲ： A and antioxidant ability indexes of patients in the two groups after the delivery at first, third and fifth day were compared. Results The serum CRP of observation group after the delivery at first, third and fifth day were （3.96 4±0. 54, 5.13 ±0. 73, 4. 32 4±0.62） mg/L, PCT were （1.82 4±0.23, 2.23 4±0.28, 1.94 4±0.25） t.tg/L, IL-6 were （11.32 4±1.58, 17.32 4± 1.97, 13.01 ± 1.73） pg/ml, and they were all higher than those in control group, AT-Ⅲ： A were （70. 18 4±3.29, 63.41 4±3.06, 67.42 4±3.17） %. They were lower than those in control group, SOD were （72.41 4±5.20, 70.06 4±5.09, 71.93 4±5.15） nU/ml, TAC were （7.26 4±0. 98, 7.03 4±0. 96, 7.59 4±1.04） kU/L, and they were all lower than those in control group, MDA were （3.39 4±0.35, 3.78 4±0.39, 3.50 4±0.33） nmol/m, MPO were （2.78 ±0.26, 3.12 4±0.35, 2.87 4±0.29） mg/L, and they were all higher than those in control group,and the change range of patients with pelvic peritonitis were bigger than those incontrol group, all P 〈0.05, there were significant differences. Conclusion The change of multiple serum factors of lying-in women with puerperal infection is in poor state,and it can effectively reflect the state of body.
出处
《宁夏医学杂志》
CAS
2013年第4期313-314,共2页
Ningxia Medical Journal
