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1741例不孕不育患者支原体感染及药敏分析 被引量:12

Analysis on mycoplasma infection and medicine sensitivity in 1 741 patients with sterility
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摘要 目的了解本地区泌尿生殖道支原体感染状况并进行药敏分析,指导临床合理用药。方法采用珠海迪尔生物工程有限公司生产的药敏试剂盒,用液体培养的方法分离鉴定解脲支原体(Uu)和人型支原体(Mh),并做12种抗生素药敏试验。结果在1 741例阳性患者中,单纯Uu感染1 548例占88.92%;单纯Mh感染57例占3.27%;Uu+Mh混合感染136例占7.81%;可见泌尿生殖道感染以Uu感染为主。药敏结果显示Uu、Mh和Uu+Mh三种感染均对强力霉素、交沙霉素、美满霉素的敏感性强。结论本地区泌尿生殖系支原体感染中,Uu感染率最高,其次为Uu合并Mh混合感染;强力霉素、交沙霉素、美满霉素可以作为目前治疗Uu、Mh和Uu+Mh三种感染的首选。 Objective To research the urogenital mycoplasma infection in this region, and analyze the sensitiv- ity in order to instruct the clinical rational administration. Methods Ul'eaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) stains were isolated and identified by liquid culture, and sensitivity test of 12 kinds of drugs were per- formed. Results In 1 741 cases, there were 1 548 cases with simple Uu infection (accounted for 88.92%), 57 cases with simple Mh infection (accounted for 3.27%), and 136 cases with Uu + Mh mixed infection (accounted for 7.81%). It showed that Uu infection was predominant form in genitourinary tract infection. Sensitivity results showed that Uu, Mh and Uu + Mh mixed infection all had high sensitivity to doxycycline, josamycin and minocy- cline. Conclusion Uu has the highest infection rate in the genitourinary mycoplasma infection, followed by Uu + Mh mixed infection. Doxycycline, josamycin, and minocycline are the first choices for the treatment of Uu, Mh and Uu + Mh infection. Mycoplasma resistant to long-term monitoring is an important basis for clinical treatment, so clinicians should reasonably choose antibiotics according to the sensitivity results.
作者 吴艳梅
出处 《检验医学与临床》 CAS 2013年第8期951-952,共2页 Laboratory Medicine and Clinic
关键词 支原体 药物敏感试验 耐药性 不孕不育 mycoplasma drug sensitivity test drug resistance sterility
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