摘要
目的评价高强度聚焦超声（HIFU）治疗肝癌的临床疗效。方法回顾35例应用HIFU技术治疗肝癌患者的临床资料、治疗前后的实验室检查、影像学检查结果及随访情况进行分析。结果治疗后AFP阳性患者术后较术前明显降低或转阴的患者占80%（24/30）;术后B超﹑CT、MRI复查肿瘤坏死的有27例,占77.1%（27/35）;肿瘤缩小者19例,占54.2%（19/35）;35例患者中治疗后,有10例患者出现局部皮肤烧伤,1例出现右侧胸腔积液。随访时间2~60个月,平均42个月,5年生存率为60%（21/35）。结论对于不宜行手术切除或不愿意手术的肝癌患者,HIFU治疗肝癌同样可取得令人满意的疗效。
【Objective】To evaluate therapeutic effect of extracorporeal high intensity focused ultrasound（HIFU） in the treatment of hepatocarcinoma.【Methods】Retrospective study was performed,which involved 35 patients with hepatocellular carcinoma treated by HIPU.The clinical data were reviewed pre-and post-HIFU,including clinical symptoms,laboratory examination data,and follow-up data.【Results】Level of serum alpha-fetoprotein（AFP） in 80% patients decreased significantly.Computed tomography（CT） and Magnetic resonance imaging showed complete coagulative necrosis of the tumors in 21 patients（77.1%）.The size of tumors decreased in 19 cases（54.2%）.Only a few patients had regional skin bum.Postoperative follow up in the HIPU was 2 to 60 months;5 year survival rate was 60%（21/35）.【Conclusion】HIFU is a new effective noninvasive method of treating hepatocellular carcinoma.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2013年第6期81-84,共4页
China Journal of Modern Medicine
关键词
高强度聚焦超声
肝细胞癌
超声治疗
high intensity focused ultrasound
hepatocellular carcinoma
ultrasound treatment
