摘要
目的观察中药干预前后咳嗽变异性哮喘(CVA)患儿指纹长度变化特点及指纹变化与血氧饱和度(SaO2)之间的关系;探讨指纹的年龄扩展应用。方法将符合本研究标准的60例CVA患儿,随机分为治疗组和对照组各30例。治疗组发作期口服温肺化痰饮,缓解期口服补肺健脾饮;对照组口服孟鲁司特钠,发作期加服氨茶碱。疗程3个月。分别收集治疗前后患儿的指纹和经皮测SaO2,观察其差异。另外收集20例正常儿童的指纹和SaO2作为健康对照。结果 CVA患儿的指纹长短与健康儿童比较,差异有统计学意义(P<0.01)。治疗组和对照组之间指纹长短比较,在治疗前和治疗后,差异均无统计学意义(P>0.05)。治疗组和对照组组内治疗前后比较,差异均有统计学意义(P<0.05)。CVA患儿和正常儿的SaO2比较,差异无统计学意义(P>0.05)。结论察看指纹长度可以作为辅助诊断CVA的一种简便、无创的方法,可为判定CVA疗效作参考,并可以推广应用至8岁。
Objective To observe the characteristics of fingerprint changes of children with cough variant asthma（CVA） before and after Chinese Medicine intervention and the relationship between the fingerprint changes and the oxygen saturation（SaO2） and to discuss age extended appli- cation of fingerprint. Methods 60 CVA patients were randomly divided into treatment group and control group, with 30 cases in each group. The treatment group was applied with Wenfeihu- atan Decoction in paroxysmal stage and Bufeijianpi Decoction in remission stage. The control group was treated with aminophylline, and montelukast sodium was added in paroxysmal stage. The 2 groups were treated for 3 months respectively. The fingerprints of children were collected and SaO2 content was measured by transcutaneous before and after treatment. In addition, the finger- prints of the 20 normal children were collected and SaO2 content was measured. Results There were significant differences in fingerprint length between the children with CVA and healthy children （P〈0.05）. There were no significant differences in fingerprint length between treatment and control groups in both before and after treatment （P〉0.05）, while there were statisti-cal differences in each group before and after treatment（P〈0.05）. There were no statistical differences in SaO2 between CVA children and normal children （P〉0.05）. Conclusion Fingerprint changes can be used as a secondary diagnosis of CVA, which is simple, objective and non-invasive. The ob- served changes in the fingerprint length can be used as one of the indicators to determine the effi- cacy of medicines and can be extended to 8-years old children.
出处
《湖南中医药大学学报》
CAS
2013年第3期52-55,共4页
Journal of Hunan University of Chinese Medicine
基金
湖南省科技厅科研基金资助项目(2010sk3014)
关键词
咳嗽变异性哮喘
指纹
虚寒证
温肺化痰饮
补肺健脾饮
Cough variant asthma
fingerprint
deficiency-cold syndrome
Wenfeihuatan De- coction
Bufeijianpi Decoction
