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线粒体DNA缺失作为辐射生物分子剂量计的研究现状

Research Progress on Radiation-Induced Deletion of Mitochondrial DNA as a Biological Molecular Dosimeter
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摘要 辐射生物剂量计,在估算个体受照剂量中起着十分重要的作用。近年来,线粒体DNA片段缺失作为一种新的辐射生物分子剂量计的可行性研究,受到越来越多的关注。本文对线粒体DNA片段缺失尤其是线粒体4977bp缺失的研究现状作一简要概述。 Radiation biological dosimeter plays an important role in estimating individual radiation dose.Recently,growing attention has been paid to the feasibility studies of mitochondrial DNA deletion as a new biological molecular dosimeter of radiation.This review summarized current research progress on mitochondrial DNA deletion,especially 4977bp deletion.
出处 《环境与职业医学》 CAS 北大核心 2013年第4期303-306,共4页 Journal of Environmental and Occupational Medicine
基金 上海市公共卫生重点学科建设项目(编号:12GWZX0401)
关键词 辐射 生物剂量计 线粒体DNA缺失 4977BP缺失 radiation biological dosimeter mitochondrial DNA deletion 4977bp deletion
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