期刊文献+

非小细胞肺癌中TFPI-2的表达及其研究进展 被引量:1

下载PDF
导出
摘要 近年来原发性肺癌的发病率和死亡率正在逐年上升,已成为当今世界上对人类健康威胁最大的恶性肿瘤,其中非小细胞肺癌(NSCLC)占所有肺癌病例数的70%~80%。当肺癌在早期即被确诊时,五年生存率约为50%。肺癌转移是临床上大多数肺癌患者的致死因素。对于诊断时没有远处转移的NSCLC患者来说,淋巴结转移提示肿瘤的预后不良,
机构地区 包头肿瘤医院
出处 《包头医学院学报》 CAS 2013年第1期120-121,共2页 Journal of Baotou Medical College
  • 相关文献

参考文献13

  • 1Miyagi Y, Koshikawa N, Yasumitsu H, et al. cDNA cloning and mR- NA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor - 2 [ J ]. J Biochem, 1994,116 ( 5 ) :939 - 942. 被引量:1
  • 2Kamei S, Kazama Y, Kuijper JL, et al. Genomic structure and pro- moter activity of the human tissue factor pathway inhibitor - 2 gene [ J ]. Biochim Biophys Acta,2001,1517 ( 3 ) : 430 - 435. 被引量:1
  • 3苗海卫(综述),罗心平(审校).组织因子途径抑制物2的研究进展[J].医学综述,2009,15(9):1286-1288. 被引量:3
  • 4Rao CN, Mohanam S, Puppala A, at al. Regulation of ProMMP - 1 and ProMMP -3 activation by tissue factor pathway inhibitor -2/ma- trix- associated serine protease inhibitor [ J ]. Biochem Biophys Res Commun, 1999,255 ( 1 ) :94 - 98. 被引量:1
  • 5Herman MP, Sukhova GK, Kisiel W, et al. Tissue factor pathway in- hibitor - 2 is a novel inhibitor of matrix metalloproteinases with impli- cations for atherosclerosis [ J ]. J Clin Invest, 2001,107 ( 9 ) : 1117 - 1126. 被引量:1
  • 6Du X, Chand HS, Kisiel W. Human tissue factor pathway inhibitor - 2 does not bind or inhibit activated matrix metaloproteinase - 1 [ J ]. Biochim Biophys Acta,2003,1621 ( 3 ) :242 - 245. 被引量:1
  • 7Chand HS, Du X, Ma D, et al. The effect of human tissue factor pathway inhibitor - 2 on the growth and metastasis of fibrosarcoma tumors in athymic mice [ J ]. Blood,2004,103 ( 3 ) : 1069 - 1077. 被引量:1
  • 8Rollin J, Regina S, Vourch P, et al. Influence of MMP -2 and MMP -9 promoter polymorphisms on gene expression and clinical outcome of non - small cell lung cancer [ J ]. Lung Cancer,2007,56 ( 2 ) : 273 - 280. 被引量:1
  • 9张玉阳,帅茨霞,郑飞云,韩义香.卵巢癌组织中组织因子途径抑制物2的表达及其临床意义[J].实用肿瘤学杂志,2007,21(4):325-327. 被引量:1
  • 10孙亚男,刘鸣,金德均,肖玉丽.TFPI-2基因表达变化与声门上喉癌侵袭转移及预后的相关性研究[J].肿瘤,2008,28(1):40-43. 被引量:4

二级参考文献59

  • 1徐勇,刘雪燕,李体远,杜珙.中国人TFPI-2基因的克隆及测序分析[J].国外医学(临床生物化学与检验学分册),2005,26(7):388-389. 被引量:5
  • 2张清华,李少林,彭志平,周祖平,李军,胡宝云,李臣基.PTEN与MMP-9在子宫内膜癌中的表达及临床意义[J].肿瘤,2006,26(5):476-479. 被引量:7
  • 3毕晓,徐勇,涂植光.中国人组织因子途径抑制物-2基因的真核表达载体的构建[J].国际检验医学杂志,2007,28(2):106-107. 被引量:5
  • 4Glahn J. Genetic variations in the human TFPI-2 gene and its promoter region by denaturing high performance liquid chmmatogrphy [ J ]. Thremb Res,2004,113 (2) :341-343. 被引量:1
  • 5Hube F, Reverdiau P, Ioehmann S,et al. Computer model of the interaction of human TFPI-2 Kunitz type sefine protease inhibitor with human plasmin [ J ]. Thromb Res ,2003,111 ( 1 ) : 197-198. 被引量:1
  • 6Chand HS, Schmidt AE, Bajaj SP, et al. Structure-function analysis of the reactive site in the first kunitz-type domain oihuman tissue factor pathway inhibitor-2 [ J ]. J Bid Chem, 2004, 279 ( 17 ) : 17500-17507. 被引量:1
  • 7Liu YY,Stack SM,Lakka SS,et al. Matrix loeallotion of tissue factorpathway inhibitor-2/matrix) associated serine protease inhibitor (TFPI-2/MSPI) involves Arglnine mediated ionie interactions with heparin and dermatan sulfate: Heparin aceelerates the activity of TFPI-2/MSPI toward plasmin [ J ]. Arch Bioehem Biophys, 1999, 370( 1 ) :112-118. 被引量:1
  • 8Hub6 F, Reverdiau P, Iochmann S,et al. Characterization and funetional analysis of TFPI-2 gene promoter in a human chorioearcinomaeell line[J]. Thromb Res,2003,109(2) :207-215. 被引量:1
  • 9Esteller M. Aberrant DNA mcthylation as a cancer inducing mechanism [ J ]. Annu Rev Pharmacol Toxicol, 2005,45 (4) : 629 -656. 被引量:1
  • 10Miyagi Y, Koshikawa N, Yasumtisu H, et al. Cdna and Mrna expression of a serine proteinase secreted by cancer cells : indentification as plas protein 5 and tissue factor pathwayinhibitor-2 [ J ]. Biochem, 1994,116 (4) :939-942. 被引量:1

共引文献10

同被引文献5

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部