摘要
目的探讨低分子肝素钙在慢性阻塞性肺疾病急性加重期的临床效果。方法选择我院慢性阻塞性肺疾病患者共112例,均为急性加重期患者。上述患者随机分为观察组和对照组。对照组给予常规治疗,观察组在常规治疗基础上给予低分子肝素钙。观察两组治疗前和治疗后血液流变学指标改变情况。结果观察组治疗后全血粘度、血浆粘度、纤维蛋白原水平分别低于对照组治疗后全血粘度、血浆粘度、纤维蛋白原水平,差异有统计学意义(P<0.05);观察组治疗后总有效率(96.4%)高于对照组总有效率(80.3%),差异有统计学意义(P<0.05)。结论低分子肝素钙能够改善慢性阻塞性肺疾病急性加重期患者血液流变学指标,提高治疗效果。
Objective To explore the clinical effect of low molecular weight heparin on the patients with acute exacerbations of chronic obstructive pulmonary disease. Methods 112 cases with acute exacerbations of chronic obstructive pulmonary disease were selected, and randomly divided into observation group and control group. The control group was given routine treatment, low molecular weight heparin calcium was used to the observation group on the base of routine treatment, changes of Blood rheology in two groups before treatment and after treatment was observed. Results Whole blood viscosity, plasma viscosity, fibrinogen levels in the observation group after treatment were lower than those in control group after treatment, the difference was statistically significant （ P 〈 0. 05 ） ; The total efficiency （ 96. 4% ） in the observation group was higher than that （ 80. 3% ） in control group, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion Low molecular heparin calcium can improve the blood rheology indexes of the patients with acute exacerbation of chronic obstructive pulmonary disease, and improve the clinical efficacy.
出处
《中国实用医药》
2013年第9期3-4,共2页
China Practical Medicine
关键词
慢性阻塞性肺疾病
急性加重期
低分子肝素钙
Chronic obstructive pulmonary disease
Acute exacerbation
Low molecular heparin calcium
