摘要
目的探讨常规超声、弹性成像及二者联合应用诊断甲状腺微小癌(TMC)的价值。方法回顾性分析140例(166枚结节)甲状腺结节患者的完整超声检查资料(包括弹性成像),观察甲状腺结节声像图,并进行评分;以病理结果为金标准,分别绘制应用常规超声(Ⅰ组)、弹性成像(Ⅱ组)及常规超声联合弹性成像(Ⅲ组)诊断甲状腺结节良恶性的ROC曲线,比较ROC曲线下面积(AUC),确定最佳诊断界点。结果Ⅰ组、Ⅱ组、Ⅲ组AUC分别为0.901、0.879及0.956。Ⅰ组与Ⅱ组间差异无统计学意义(Z=0.593,P=0.553);Ⅰ组与Ⅲ组间差异有统计学意义(Z=3.936,P=0.0001);Ⅱ组与Ⅲ组间差异有统计学意义(Z=2.651,P=0.008)。Ⅰ、Ⅱ、Ⅲ组最佳诊断界点分别为5分、3分、7分,其敏感度与特异度分别为84.9%与86.0%、87.7%与84.9%、95.6%与82.2%。结论常规超声及弹性成像诊断TMC均有较高准确性,二者联合应用可进一步提高超声诊断效能,降低漏诊率。
Objective To explore the value of conventional ultrasonography, elastography and the combination of the two methods for diagnosis of thyroid microcarclnoma （TMC）. Methods Integrated sonographic data （including elastography） of 140 patients （166 nodules） with thyroid nodule were analyzed retrospectively, and sonogram of these cases were ob- served and scored carefully. All the lesions were confirmed by pathology. ROC curves were drawn to distinguish benign and malignant lesions according to the features of conventional ultrasonography （group I ）, elastography （group lI ） and the combination of them （group Ill ）, and the area under the curve （AUC） of the three groups were eompared, the cut-off val- ues were defined. Results The AUC of group I , Ⅱ and Ⅲ was 0. 901, 0. 879 and 0. 956, respectively. The difference between group Ⅰ and Ⅱ was not statistically significant （Z：0. 593, P：0. 553）, while between group Ⅰ and Ⅲ , was sta- tistically significant （Z：3. 936, P：0. 0001）, so as between group Ⅱ and Ⅲ （Z：2. 651, P^0. 008）. The cut-off value of group I , Ⅱ and Ⅲwas 5, 3 and 7, respectively, and the sensitivit and specificity was 84.9% and 86.0%, 87.7% and 84.9%, 95.6% and 82.2%, respectively. Conclusion Both conventional US and elastography show considerable accuracy for diagnosis of TMC. Combination of them can elevate diagnosis efficacy of ultrasound, improve the sensitivity and de- crease miss diagnosis.
出处
《中国医学影像技术》
CSCD
北大核心
2013年第4期528-531,共4页
Chinese Journal of Medical Imaging Technology
关键词
超声检查
弹性成像技术
甲状腺结节
甲状腺肿瘤
Ultrasonography
Elasticity imaging techniques
Thyroid nodule
Thyroid neoplasms
