摘要
结直肠癌是最常见的恶性肿瘤之一,其发生由遗传和环境等诸多因素相互作用所致,是一个涉及多基因、多阶段的复杂过程。本文就结直肠癌发生机制包括染色体不稳定(CIN)、微卫星不稳定(MSI)、CpG岛甲基化表型(CIMP)等的研究进展作一综述。
Colorectal cancer is one of the most common malignant tumors. The genesis of colorectal cancer is the result of interaction between genetic and environmental factors, and is a muhi-gene, multi-step process. This article reviewed the advances in study on pathogenesis of colorectal cancer, including chromosome instability （CIN）, microsatellite instability （MSI） and CpG island methylator phenotype （CIMP）.
出处
《胃肠病学》
2013年第3期188-190,共3页
Chinese Journal of Gastroenterology
关键词
结直肠肿瘤
分子作用机制
治疗
Colorectal Neoplasms
Molecular Mechanisms of Action
Therapy
