期刊文献+

氟比洛芬酯复合舒芬太尼用于老年腹部手术患者术后镇痛的效果 被引量:1

Efficacy of flurbiprofen axetii combined with sufentanil for postoperative analgesia in elderly patients with abdominal surgery
原文传递
导出
摘要 目的探讨氟比洛芬酯复合舒芬太尼用于老年腹部手术后镇痛的有效性与用法。方法择期老年腹部手术患者76例,随机分成4组,B、C、D组于切皮前静脉滴注氟比洛芬酯100mg,A、B、C、D组PCIA配方分别是舒芬太尼0.5、1、1.5、2μg·kg^-1,加入氟比洛芬酯2mg·kg^-1、托烷司琼5mg,记录各时间点VAS、Ramsay评分和按压次数。结果B、C、D组VAS评分较A组低,C、D组VAS评分较B组低。A组Ramsay评分较C、D组高,B组Ramsay镇静评分较C、D组升高。A、B组按压次数较C、D组增多,B、C组满意率较A、D组高。结论术前给予氟比洛芬酯具有预先镇痛效果,PCIA配方以C组为宜。 Objective To explore the efficacy and methods of flurbiprofen axetil combined with sufentanil for postoperative analgesia in elderly patients with abdominal surgery. Methods Seventy- six patients underwent abdominal surgery were randomly divided into four groups. Group B, C and D received 100 mg flurbiprofen axetil before skin incision. The PCIA prescriptions were sufentanil 0.5, 1, 1.5 and 2μg·kg^-1 respectively, adding flurbiprofen axetil 2 mg·kg^-1 and tropisetron 5 mg in group A, B, C and D. VAS, Ramsay scores and press times were recorded. Results Compared with group A, VAS was low in group B,C and D. Compared with group B, VAS was low in group C and D. Ramsay sedation scores in group A were higher than that in group C and D. Ramsay sedation scores in group B were higher than that in group C and D. The press times in group A and B were higher than that in group C and D. Compared with group A and D, the satisfaction rates were high in group B and C. Conclusion Flurbiprofen axetil injection can produce pre-emptive analgesia effect and the analgesic effect in group C is better than that in the other groups.
出处 《实用疼痛学杂志》 2012年第6期436-438,共3页 Pain Clinic Journal
关键词 氟比洛芬 舒芬太尼 老年人 疼痛 手术后 镇痛 Sufentanil Flurbiprofen Aged Pain, postoperative Analgesia
  • 相关文献

参考文献5

二级参考文献22

  • 1徐国柱,李晓玲,段砺瑕,朱天岳,谢启伟,周应芳,王冰,邓艳萍,沈黎阳,袁旭.氟比洛芬酯脂微球载体注射液治疗中度术后疼痛的Ⅱ期临床试验[J].中国新药杂志,2004,13(9):846-848. 被引量:258
  • 2赵卫华,黄慧玲,黄楹,徐翔,莫立冬.蛛网膜下腔出血并迟发性脑血管痉挛大鼠脑能量代谢与脑血流量变化的实验研究[J].中国现代神经疾病杂志,2007,7(2):146-151. 被引量:10
  • 3[1]Ohmukai O.Lipo-NSAID preparation[J].Adv Drug Deliv Rev,1996,20(2-3):203-207. 被引量:1
  • 4[4]Kuriyama K,Hiyama Y,Aoyama Y,et al.Pharmacological studies of a non-steroidal analgesic and antipyretic drug of LFP83[J].Nippon Yakurigaku Zasshi,1989,93(2):61-73. 被引量:1
  • 5[6]Davis NM.Clinical pharmacokinetics of flurbiprofen and its enantiomers[J].Clin Pharmacokinet,1995,28(2):100-114. 被引量:1
  • 6[7]Mikawa K,Nishina K,Maekawa N,et al.Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery[J].Can J Anaesth,1997,44(1):95-98. 被引量:1
  • 7[8]Machida K,Tsutsui T,Kaneko A,et al.Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil[J].Jpn J Anesth,2001,50(4):425-428. 被引量:1
  • 8Hocke J,Tonner PH,Bollert P,et al.Propofol/remifentanil vs sevoflurane/remifentanil for long lasting surgical procedures:a randomised controlled trial.Anaesthesia,2006,61:752-757. 被引量:1
  • 9Duffy CM,Matta BF.Sevoflurane and anesthesia for neurosurgery:a review.J Neurosurg Anesthesiol,2000,12:128-140. 被引量:1
  • 10Kaike K,Jaakko W,Langsjo,et al.Effects of sevoflurane,propofol,and adjunct nitrous oxide on regional cerebral blood flow,oxygen consumption,and blood volume in humans.Anesthesiology,2003,99:603-613. 被引量:1

共引文献657

同被引文献11

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部