摘要
目的探讨江苏(简称江)、浙江(简称浙)、上海(简称沪)、安徽(简称皖)地区18～22周岁男性血镉、尿汞参考区间,为消防员职业健康体检的重金属筛查提供更为切合实际的参考标准。方法使用原子吸收分光光度法对1 683名新入伍消防员进行血镉测定。使用酸性氯化亚锡还原法进行尿汞测定,结果采用肌酐(Cr)校正。再对血镉、尿汞值进行统计学分析,参考区间按P0～P95计算;同时分地域、是否吸烟比较。结果江浙沪皖地区18～22周岁男性血镉值呈正偏态分布,参考区间为0～6.70μg/L;尿汞值呈正偏态分布,参考区间为0～3.00μg/g Cr;地域之间比较差异无统计学意义(P>0.05);吸烟与非吸烟组比较差异有统计学意义(P<0.05)。结论血镉、尿汞参考区间应区分不同地区、不同年龄建立参考区间。
Objective To investigate the reference intervals of blood cadmium and urine mercury in Jiangsu, Zhejiang, Shanghai and Anhui regions among 18-22-year-old males, and to provide realistic reference standards for fiirefighter occupational health examination of heavy metal screening. Methods The atomic absorption spectrophotometry was used for blood cadmium determination in 1 683 new firefighters. The acidic stannous chloride reduction method was used for the deteimination of urine mercury, and the results were calibrated by creatinine （Cr）. The blood cadmium and urine mercury values were analyzed statistically. The results were classified and analyzed comparatively according to regions and smoking with reference intervals calculated by P0-P95. Results In Jiangsu, Zhejiang, Shanghai and Anhui regions among 18-22-year-old males, the blood cadmium values were positively skewed distribution, and the reference interval was 0-6.70 ug/L. Urine mercury values were positively skewed distribution, and the reference interval was 0-3.00 ug/g Cr. The regional comparison had no statistical significance （ P 〉 0.05 ）. The comparison between smoking group and non-smoking group had statistical significance （ P 〈 0.05 ）. Conclusions The reference intervals of blood cadmium and urine mercury should be established and classified between different regions and different ages.
出处
《检验医学》
CAS
2013年第3期203-206,共4页
Laboratory Medicine
基金
国家自然科学基金(81100585)
关键词
血镉
尿汞
参考区间
Blood cadmium
Urine mercury
Reference interval
