摘要
目的:探讨B型利钠肽(BNP)在评估慢性房颤患者左心房血栓形成中的临床价值。方法:对65例慢性房颤患者实施经食管超声检查,根据有无左心房血栓分组,检测并比较患者的BNP及其他临床资料。结果:左房血栓组的血浆BNP水平高于无左房血栓组(93.27±22.13)ng/L对(54.19±19.04)ng/L。多变量回归分析表明,高血浆BNP水平是慢性房颤患者发生左房血栓的独立预测指标(OR=1.01,95%CI:1.00～1.15,P=0.04)。结论:血浆BNP水平可作为预测慢性房颤患者左房血栓的指标。
Objective： This study aims to examine the clinical value of B-type natriuretic peptide （BNP）for left atrial thrombosis in patients with chronic atrial fibrillation. Methods： A total of 65 patients with chronic atrial fibrillation were divided into two groups according to left atrial thrombosis by transesophageal echocardiography （TEE）. Plasma levels of BNP and other clinical data were recorded and analysed. Results： Thirty-one patients had left atrial thrombus （LAT） by TEE. Baseline characteristics in patiens with LAT （positive group ） and those without LAT （negative group） were similar. Mean BNP levels were significantly higher in positive group than negative group [（93. 27 ± 22.13） ng/L vs. （54. 19 ± 19. 04） ng/L, P 〈 0. 05]. Multivariate logistic regression analysis demonstrated that BNP level was a predictor for LAT independent of the left atrial diameter （OR = 1.0l, 95%CI： 1. 00 - 1. 15, P = 0. 04）, as well as CHADS2 scores. Conclusion： BNP levels predict independently left atrial thrombosis in patiens with chronic atrial fibrillation.
出处
《国际心血管病杂志》
2013年第2期122-123,共2页
International Journal of Cardiovascular Disease
关键词
B型利钠肽
心房颤动
左房血栓
B-type natriuretic peptide
Atrial fibrillation
Left atrial thrombus
