摘要
目的:研究慢性原发性肾脏病3期患者肾虚证与肾病理的相关性。方法:分析97例CKD3期患者肾虚证证候积分与肾病理小球、小管间质、血管及与活动、慢性病变积分的相关性。结果:肾虚证重度患者肾病理katafuchi评分总积分高于轻证患者、Andreoli评分硬化小球评分高于轻度组患者、Andreoli评分细胞新月体的积分高于轻、中度组患者;二联证(肾虚+瘀痹)、三联证(肾虚+瘀痹+风湿)Andreoli评分的活动性指数总积分及间质炎细胞积分明显高于单纯肾虚证患者;三联证的活动性指数总积分尚高于二联证(肾虚+风湿);三联证(肾虚+瘀痹+风湿)的Andreoli评分慢性化指数总积分和纤维新月体的积分均明显高于单纯肾虚证组,二联证(肾虚+瘀痹)的纤维化积分高于单纯肾虚证组。结论:肾虚证的严重程度与肾病理慢性化指数相关,多联证患者肾病理相对重,且呈慢性、活动性病变的多样性表现。
Objective： Correlation study between Syndrome - Manifestation of the Deficiency of Kidney - Qi and Yin （Blood） syndrome and renal pathology in patients with Chronic kidney disease -3 stage. Methods ：To analyze the correlations between the score of deficiency syndrome and the score of glomerular, tubulointerstitial, vascular, active and chronic disease of renal pathology in 97 CKD -3 stage patients. Results： Patients with severe deficiency syndrome have higher pathological total score （kat＇afuchi score）, Glomerular sclerosis score（ Andreoli score） and cellular crescentic＇ s score than patients with mild deficiency syndrome. Pa- tients who suffer from two or three syndromes display higher scores than patients with simple deficiency syndrome in many aspects, in- eluding activity index total score, Interstitial inflammatory cell score, chronic index total score and fiber crescentic score （ Andreoli score）. Conclusion：The severity of deficiency syndrome is related to the chronic index of the renal pathology. Patients with multi syn- dromes are proved to have more severe syndromes and more varieties of manifestations in chronic and acute disease.
出处
《中国中西医结合肾病杂志》
2013年第2期124-126,共3页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
"十一五"国家科技支撑计划项目(No.2006BAI04A07)
关键词
慢性肾脏病3期
肾虚证
病理
研究
CKD- 3 stage Deficiency syndrome Renal Pathology Research
