摘要
目的探讨超声弹性应变比值(SR)对甲状腺结节良恶性的鉴别诊断价值。方法 97例甲状腺结节患者,其中良性65例,恶性32例,采用超声弹性成像技术测量周围组织与结节的SR,比较良性与恶性结节间SR的差异,通过建立受试者工作特性曲线(ROC)来评价SR诊断甲状腺良恶性结节的价值。结果 65例良性及32例恶性甲状腺结节的SR值分别为1.41±0.73及6.57±4.34,差异有统计学意义。应用ROC曲线评价SR诊断甲状腺恶性结节的曲线下面积为0.982,取SR阈值为2.73时,敏感度、特异度、准确性、阳性预测值及阴性预测值分别为96.88%、96.92%、96.91%、93.94%和98.44%。结论超声弹性参数SR对甲状腺结节的良恶性鉴别有较好的应用价值。
Objective To explore the value of strain ratio （SR） in differentiating benign from malignant thyroid nodules. Methods Ninety - seven patients with benign （n = 65 ） or malignant （n = 32） thyroid nodules were enrolled in the study. The SR of normal surrounding tis- sues to thyroid nodules was calculated by ultrasonic elastography, and SRs of benign and malignant thyroid nodules were compared with independ- ent - samples T test, the diagnostic value of SR was evaluated by receiver operating characteristic curve. Results SRs of benign and malignant thyroid nodules were respectively 1.41 -sO. 73 and 6. 57 ＋4. 34, which had significant difference between them. The area under the curve was 0. 982 for SR with elnsography , took SR threshold of 2.73, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 96. 88%, 96. 92%, 96.91%, 93.94% and 98.44% respectively. Conclusion SR is an effective elasticity parameter and has good application value in differentiating benign from malignant thyroid nodules.
出处
《临床和实验医学杂志》
2013年第7期495-497,共3页
Journal of Clinical and Experimental Medicine
基金
北京友谊医院科研启动基金资助项目
