摘要
猪巨细胞病毒(Porcine Cytomegalovirus,PC-MV)是由疱疹病毒科β疱疹病毒亚科巨细胞病毒属的一种[1]。该病毒遍布全球[2],猪感染该病也是普遍存在,在北美、欧洲和日本,90%以上的猪群曾受到感染。对成年猪只通常只呈现隐性感染,而对3周齡以下仔猪常常诱发致命性的全身感染[3]。
Porcine Cytomegalovirus （PCM） is one of βCytomegalovirus subfamily in Herpesviruses family. Porcine cytomegalovirus, a beta herpesvirus, is recognized as the causative agent of inclusion body rhinitis of young swine. The PCMV has been documented to cause runting, poor weight gain, pneumonia, and rhinitis in nursery age pigs. The virus also has been shown to cause reproductive failure when immunologically negative females are exposed to the virus during pregnancy. Porcine cytomegalovirus is ubiquitous in swine producing regions throughout the world and is thought to be immunosuppressive. Persistence of virus infection in a cycle of latency and recrudescence under stressful conditions is considered to be an ongoiag problem in affected herds. Xenotransplantation of swine tissues has been proposed as a way of alleviating the shortage of human organs for transplantation. PCMV is activated in pig-to-primate xenografts. It is very significant whether PCMV infects human or not.
出处
《中国兽医杂志》
CAS
北大核心
2013年第3期82-85,共4页
Chinese Journal of Veterinary Medicine
