紫杉醇联合顺铂5-FU治疗原发灶不明恶性肿瘤一例分析
摘要
原发灶不明恶性肿瘤(unknown primary tumor,UPT)是一种异源性发生的,首先表现为转移性病灶、确诊时找不到原发灶的一类恶性肿瘤,既往称之为原发灶不明的转移癌、来源不明的转移癌(MUO)、隐匿性癌等。其发病率约占实体瘤的2.3%~42%,文献E33报道,UPT的中位生存时间仅为4.8个月。本科近年收治1例UPT伴全身多发转移患者,报告如下。
参考文献14
-
1Mevio E, Gorini E, Sbrocca M, et al. The role of positron e- mission tomography (PET) in the management of cervical lymph nodes metastases from an unknown primary turnout. Acta Otorhinolaryngol Ital, 2004, 24(6): 342-347. 被引量:1
-
2Pavlidis N,Fizazi K. Cancer of unknown primary(CUP). Crit Rev Oncol Heraatol, 2005,54 (3) : 243-250. 被引量:1
-
3王成锋,田艳涛,张建伟.不明原发灶肿瘤1273例报告[J].中国微创外科杂志,2007,7(11):1072-1074. 被引量:5
-
4Van de Wouw AJ ,Janssen-Heijnen ML, Coebergh JW, et al. Epidemiology of unknown primary tumours: incidence and population-based survival of 1285 patients in Southeast Neth- erlands,1984-1992. Eur J Cancer,2002,38(3) :409-413. 被引量:1
-
5Shaw PHS,Adams R,Jordan C,et al. A clinical review of the investigation and management of carcinoma of unknown pri- mary in asingle cancer network. Clin Oncol, 2007,19 ( 1 ) : 87- 95. 被引量:1
-
6Vant-Veer LJ,Weigelt B. Road map to metastasis. Nat Med, 2003,9 (8) : 999-1000. 被引量:1
-
7Bugat R, Bataillard A, Lesimple T, et al. Summary of the standards,options and recommendations for the management of patients with carcinoma of unknown primary site. Br J Cancer, 2003,89 Suppl 1 : $59-$66. 被引量:1
-
8储大同主编..当代肿瘤内科治疗方案评价 第2版[M].北京:北京大学医学出版社,2004:400.
-
9Greco FA, Burris HA, Erland EB, et al. Carcinoma of un- known primary site. Long term follow-up after treatment with paclitaxe| earboplatin and etoposide. Cancer, 2000, 89 26552660. 被引量:1
-
10和钢,李锦.原发灶不明转移瘤的临床诊治与转归[J].现代实用医学,2002,14(9):479-480. 被引量:3
二级参考文献37
-
1陈华,黄建瑾.原发灶不明癌24例临床分析[J].中国实用医药,2007,2(36):39-41. 被引量:5
-
2吴毅.原发灶不明颈部转移性鳞癌的诊治[J].中华肿瘤防治杂志,2006,13(12):881-883. 被引量:9
-
3[1]Greco FA, Hainsworth JD. Tumors of unknown origin[J]. CA,1992,42:96. 被引量:1
-
4[2]Sporn JR,Greenberg BR. Empirical chemotherapy for adenocarcinoma of unknown primary tumor site[J]. Semin Oncol,1993,20:261. 被引量:1
-
5[3]Treat J, Falchuk SG, Tremblay C, et al. PhaseⅡtrial of methotrexate-FAM in adenocarcinoma of unknown primary[J]. Eur J Cancer Clin Oncol,1989,25:1053. 被引量:1
-
6[4]Hainsworth JD,Wright EP,Gray GF Jr,et al. Poorly differentiated carcinoma of unknown primary site:correlation of light microscopic findings with response to cisplatin-based combination chemotherapy[J]. J Clin Oncol, 1987,5:1272. 被引量:1
-
7[5]Weir L,Keane T,Cummings B,et al. Radiation treatment of cervical lymph node metastasis from an unknown primary:an analysis of outcome by treatment volume and other prognostic factors[J].Radiother Oncol,1995,35:206. 被引量:1
-
8[6]Carlson LS,Fletcher GH,Oswald MJ. Guidelines for the radiotherapeutic techniques for cervical metastases from an unknown primary[J]. Int J Radiat Oncol Biol Phys,1986,12:2101. 被引量:1
-
9[1]Abbruzzese JL,Abbruzzese MC,Lenzi R,et al.Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin.J Clin Oncol,1995,13(8):2094 -2103. 被引量:1
-
10[2]Pavlidis N,Fizazi K.Cancer of unknown primary (CUP).Crit Rev Oncol Hematol,2005,54(3):243-250. 被引量:1
共引文献11
-
1吴小红,华东,陈晓萍.原发灶不明的骨转移性癌24例分析[J].肿瘤防治杂志,2004,11(4):446-447. 被引量:3
-
2解亦斌,刘方伶,田艳涛,王成锋,单毅,赵东兵,赵平.升结肠癌跳跃式转移至右颈部及左腋下淋巴结1例分析[J].中国肿瘤临床,2009,36(10):593-596. 被引量:4
-
3张智显,马峻峰,付登礼,陈嘉勇.不明原发灶颈部转移癌的诊断和治疗[J].医学综述,2010,16(10):1491-1493. 被引量:1
-
4崔艳艳.多西紫杉醇联合顺铂治疗原发灶不明癌的疗效观察[J].现代肿瘤医学,2010,18(10):2057-2058. 被引量:5
-
5迪吉.多西紫杉醇联合顺铂治疗原发灶不明癌的疗效观察[J].临床合理用药杂志,2012,5(18):57-57. 被引量:3
-
6王珍珍,路太英,彭湃,李珊珊.恩度联合全身化疗治疗原发灶不明癌的临床观察[J].中国实用医刊,2013,40(11):51-52. 被引量:3
-
7潘赛英,陈倩琪,仇蓉,简素娟.多西紫杉醇联合顺铂治疗原发灶不明癌疗效观察[J].中国实用医刊,2013,40(13):69-70. 被引量:1
-
8徐梦姗,高峰,郑坚,杨金坤.紫杉醇联合顺铂治疗原发灶不明恶性肿瘤一例[J].江苏医药,2013,39(14):1727-1727. 被引量:3
-
9张莹,王洪儒.原发灶不明的颈部转移癌之诊治思路[J].中国肿瘤,2013,22(9):724-727. 被引量:3
-
10朱晶晶,李征洋,陈海飞,李洁,张宇皓,吴天勤,沈红石,唐杰庆,王静,秦龙梅,金玲娟.酷似急性白血病的乳腺胚胎型横纹肌肉瘤一例并文献复习[J].肿瘤研究与临床,2015,27(7):469-472. 被引量:2
-
1唐学洵.隐匿性甲状腺癌[J].中国普通外科杂志,1996,5(3):158-159. 被引量:1
-
2金钰玛,方军初.甲状腺癌的超声图像特征分析[J].苏州大学学报(医学版),2008,28(5):831-831. 被引量:12
-
3王益民,王磊.隐匿性乳腺癌两种治疗方法比较(附19例报道)[J].蚌埠医学院学报,2004,29(1):21-22.
-
4周慧霞.11例甲状腺微小乳头状癌的临床病理分析[J].实用癌症杂志,2011,26(1):98-98. 被引量:5
-
5韩学东,甄林林.隐匿性乳腺癌外科治疗[J].中国综合临床,2008,24(5):481-482. 被引量:1
-
6余英豪.不明原发部位肿瘤的研究进展[J].实用肿瘤杂志,2005,20(5):454-457. 被引量:1
-
7王忠平.隐匿性甲状腺癌24例临床分析[J].健康大视野(医学版),2013,21(12):1212-1212.
-
8刘明辉,田雪合.隐匿性甲状腺癌24例临床分析[J].郑州大学学报(医学版),2007,42(5):1015-1016. 被引量:3
-
9潘明,徐金发,刘飞,宋文灿,刘春林,陈国卿.顺铂联合足叶乙甙治疗原发灶未明转移癌的临床观察[J].中华全科医学,2003,5(3):216-217.
-
10陈振东,熊福星,胡家骅.MUO的诊断问题[J].肿瘤防治研究,1991,18(2):125-127.