摘要
目的探讨分水岭脑梗死(CWI)的病因、诊断及急性期治疗的优化方案,为CWI对因治疗提供依据。方法 60例CWI患者随机分为尤瑞克林治疗组(治疗组)和对照组。分别在治疗前、治疗后第7和14天进行NIHSS评分。并根据颈部B超、头颅MRI、MRA及DSA分析评估CWI患者的颅内外血管狭窄情况进行病因分型。结果 CWI患者伴有相应部位颅内外血管狭窄(>50%)53/60例(88.3%),在病因分型上绝大部分CWI属于大动脉粥样硬化型脑梗死。治疗组与对照组治疗前后NIHSS评分差异有统计学意义(P<0.05);治疗组与对照组治疗前后差值间比较差异有统计学意义(P<0.05);治疗组临床有效率为93%,对照组有效率为70%,两组间差异有统计学意义(P<0.05)。结论 CWI与颅内外血管狭窄明显相关。根据病因分型,大部分CWI属于大动脉粥样硬化型脑梗死。尤瑞克林对急性期CWI治疗效果佳。
Aim To study the etiology, diagnosis and treatment of cerebral watershed infarction（CWI）, which provide a basis for etiological treatment in future. Methods Got the NIHSS scores before and after the treatment at day 7 and day 14 respectively, 60 patients were divided randomly into a urinary kallidinogenase treatment group and a control group. According to B ultrasound of cervical part, head MRI, MRA and DSA, the states of patients＇ intracranial or extracranial vascular stenosis could be analyzed and assessed, and divided into etiologic subtypes as far as possible. Results There were 53 CWI patients （88.3%） with intracranial or extracranial vascular stenosis of corresponding parts. Most of them were cerebral infarction of artery atherosclerosis in etiologic subtypes. There was statistical significant difference （P〈0.05） of NIHSS scores between the treatment group and the control group. The clinical effective rate of the treatment group was 93%, the control was 70%. There was statistical significant difference （P〈0.05）. Conclusion CWI was closely related with intracranial or extracranial vascular stenosis. Most of CWI were cerebral infarction of artery atherosclerosis. Compared with the control, urinary kallidinogenase was effective for the watershed area of acute myocardial infarction＇s stratment.
出处
《中国临床神经科学》
2013年第2期172-177,共6页
Chinese Journal of Clinical Neurosciences
关键词
影像学
尤瑞克林
分水岭脑梗死
imaging
urinary kaUidinogenase
cerebral watershed infarction
