摘要
目的探讨角膜塑形镜对患者角膜形态及代谢功能的影响。方法随机选取60例配戴角膜塑形镜真性近视患者,年龄8～12岁,近视度数-0.75～-3.50DS(散光转化成等球计算),在戴镜前、戴镜后1d、1周、1个月、3个月、6个月检查角膜曲率、厚度及内皮计数,只取右眼数据用重复性方差分析进行统计学分析。结果患者角膜曲率和角膜中央区厚度在3个月内变平明显,3个月后趋于稳定,差异有统计学意义(P<0.05);角膜内皮镜检查中角膜内皮细胞密度有轻度降低,但差异无统计学意义(P>0.05)。结论角膜塑形镜配戴在戴镜3个月内对角膜曲率及厚度改变较大,后期趋于稳定。长期配戴角膜塑形镜者角膜内皮计数在正常范围,说明对角膜代谢影响小。角膜塑形镜用于控制近视发展从长期来看是安全有效的。
Objective To observe the influence on corneal morphology and metabolic function after treatment by or- th0keratology. Methods Randomly selected 60 cases of true myopia patients wearing orthokeratology lens, age between 8-12 years, the myopia between -0.75 DS to -3.50 DS （Astigmatism into balls calculation）, to check the curvature of the cornea, the thickness and endothelium before wearing glasses, wearing glasses one week, one month, three months, six months. Took only the right-eye data for statistical analysis of repeatability variance analysis. Results The curva- ture of the patient＇s cornea and central corneal thickness flattened apparent in the first three months, later stabilized. The difference was statistically significant （P 〈 0.05）. The average area of the corneal endothelial cells and cell coeffi- cient of variation had no significant increase in the microscopic examination of the corneal endothelium, and the corneal endothelial cells hexagon ratio had no significantly lower （P 〉 0.05）. Conclusion Major changes in corneal curvature and thickness after treatment of orthokeratology is between first three months, later tends stable. Long-term wear orthokeratology lens corneal endothelial count is in the normal range, shows small impact on corneal metabolism. This shows that orthokeratology lens is used to control the development of myopia is safe and effective in the long run.
出处
《中国现代医生》
2013年第5期159-160,共2页
China Modern Doctor
关键词
角膜塑形镜
角膜曲率
角膜厚度
内皮细胞计数
Orthokeratology
Corneal curvature
Corneal thickness
Endothelial count
