摘要
C=N异构化作为一种新型的传感机制,自2007年被报道以来,已经被广泛应用于荧光化学传感器分子的设计之中,并表现出良好的传感性能。对于含有C=N双键的化合物分子,C=N的异构化会加剧分子的激发态的非辐射跃迁,从而使得其荧光淬灭。当其与特定的客体分子相互作用时,C=N的异构化会受到抑制,使得分子的荧光恢复,从而实现对这种客体分子的检测。综述了C=N异构化这种新型的荧光传感机制的研究进展,包括这种传感机制的基本原理,其在阴、阳离子及中性分子检测中的应用,并展望了该领域的发展趋势。
As a new emerging signaling mechanism, C=N isomerization has been widely utilized in the design of novel fluorescent chemosensors with well performance since it was reported in 2007. It is found that compounds containing unbridged C=Nbonds were usually non-fluorescent as C=N isom- erization was the predominant decay process of excited states. However, compounds con＊aining a cy- clic C=N bond or complexing with a guest species to restrict the rotation of C=N bond would be strongly fluorescent. Then, it is expected that luminescence turn-on sensors toward specific analytes can be sophisticatedly designed by virtue of the suppression of C=N isomerization. Research progres- ses including basic principle of sensing mechanisms and application in the detection of cations, anions as well as neutral molecular are stated. The trend is looked ahead as well.
出处
《精细石油化工》
CAS
CSCD
北大核心
2013年第2期68-72,共5页
Speciality Petrochemicals
