摘要
目的 探讨远端胃在非营养液排空中的作用。方法应用γ闪烁成像仪和^（９９ｍ）锝－植酸钠组成的非营养液核素餐，对３组ＳＤ大鼠［正常组（ＮＧ）、剖腹探查组（ＬＧ）、远端胃切除、胃十二指肠吻合组（Ｂｉｌｌｒｏｔｈ Ⅰ ｇｒｏｕｐ，ＢＩＧ）］进行不同时期胃液体排空功能测定。结果ＮＧ大鼠在１６周内胃液体排空无明显变化（Ｐ＞０．０５）；ＬＧ大鼠在术后４周内胃液体排空存在延长现象（Ｐ＜０．０１），第８周才基本恢复至术前标准（Ｐ＞０．０５）；ＢＩＧ大鼠在第１６周胃液体排空仍没恢复到术前标准（Ｐ＜０．０１）。结论剖腹探查能暂时抑制胃非营养液排空；远端胃在非营养液排空中起着重要作用。
Objective To explore the role of distal stomach in the gastric emptying of non-nutrient liquid. Methods With ^(99m)Tc-PHY 0. 34MBq labelled non-nutrient liquid feed and gamma scintillating imaging apparatus SPECT, the gastric liquid emptying function of 21 SD rats, that were randomly divided into three groups: the normal group(NG) (n = 7); the laparotomy group (LG) (n = 7); Billroth Ⅰ group (BIG) (n = 7), were performed every 4 weeks. Results (1)NG showed no significant changes in gastric liquid emptying within 16 weeks(P > 0.05). (2)In LG the functions of gastric liquid emptying was delayed to compare to the values before surgery at the 4th week after surgery(P < 0.01 ). At the sib postoperative week, these data became the values before surgery(P > 0.05). (3) At the 16th week BIG still showed a significantly difference to the values before surgery (P < 0.01 ). Conclusions (1) Laparotomy can temporarily inhibit the emptying of non-nutrient liquid in stomach. (2)The distal stomach plays an important role in the gastric non-nutrient liquid emptying.
关键词
远端胃
胃排空
非营养液
Distal stomach Gastric emptying Non-nutrient liquid
