摘要
目的探讨肿瘤科住院患者中心静脉导管(CVC)感染的相关危险因素,为其临床的预防提供参考依据。方法共纳入120例肿瘤科的住院患者,均放置CVC,详细记录患者的相关信息,并根据其是否发生感染分为两组,应用多因素回归分析进行相关因素分析。结果 120例患者中有10例患者发生CVC感染,发生率为8.3%;CVC发生感染的单因素分析结果显示,感染组多腔导管及患有糖尿病史的发生率分别为80.0%、70.0%,非感染组分别为35.5%、36.4%,两组差异有统计学意义(P<0.05);感染组患者导管留置时间(10.1±1.3)d,白蛋白(29.1±3.1)g/L、低密度脂蛋白胆固醇(3.6±2.3)mmol/L、甘油三酯(2.4±0.3)mmol/L、总胆固醇(5.5±0.7)mmol/L水平,非感染组患者分别为(6.3±1.2)d、(36.8±4.2)g/L、(5.4±3.1)mmol/L、(1.6±0.5)mmol/L、(4.6±0.5)mmol/L,两组比较差异有统计学意义(P<0.05);进一步校正相关因素,结果表明,导管留置时间长、导管管腔多是肿瘤科患者发生CVC感染的独立危险因素(P<0.05)。结论肿瘤科CVC感染的发生与导管留置时间长、导管管腔多存在密切的相关性,是其发生的独立危险因素,在临床护理过程中,要严格进行皮肤的局部护理,可以避免感染并发症的发生,促进患者的康复。
OBJECTIVE To explore the related risk factors of central .venous catheter （CVC） infections in the hospitalized patients of the oncology department so as to provide basis for the clinical prevention. METHODS A total of 120 cases of hospitalized patients in the oncology department were enrolled in the study, all the patients were placed with CVC, the related information was recorded, the patients were divided into two groups according to the infection status , and the multivariate regression analysis was performed. RESULTS Of 120 cases of pa- tients, the CVC infections occurred in 10 cases with the incidence rate of 8.3%. The univariate analysis showed the incidence rates of the CVC infections in the patients with multi-cavity catheter and the patients with diabetes history the infection group were 80.0 % and 70.0 %, respectively and that the incidence rates of the non-infection group were 35.5% and 36.4%, respectively, the difference between the two groups was statistically significant. The catheter indwelling time. of the infection group was （10.1±1.3） days, the non-infection group （6.3±1.2） days; the albumin level of the infection group was （29.1±3.1） g/L, the non-infection group （36.8±4.2） g/L; the LDL-C level of the infection group was （3.6 ± 2.3） mmol/L, the non-infection group（5.4±3.1） mmol/L; the TG level of the infection group was （2.4±0.3） mmol/L, the non-infection group （1.6 ±0.5） mmol/L ; the TC level of the infection group was （5. 5- 0. 7） mmol/L , the non-infection group （ 4.6±0. 5） mmol/L; the difference between the two groups was statistically significant （P〈0.05）. The results of further correction of the related factors indicated that the long term of catheter indwelling and multiple-cavity catheter were the independent risk factors for the CVC infections in the patients of oncology department （P 〈0. 05）. CONCLUSION The incidence of the CVC infections in the patients of oncology department is closely related to the long term of cathet
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第7期1529-1531,共3页
Chinese Journal of Nosocomiology
关键词
肿瘤科
感染
中心静脉导管
危险因素
多因素分析
Oncology department
Infection
Central venous catheter
Risk factor
Multivariate analysis
