摘要
目的探讨中心静脉导管留置引流并心包腔内注射奈达铂治疗恶性心包积液的疗效。方法将16例有大量心包积液的患者在彩超定位引导下行心包穿刺并留置中心静脉导管,待引流完心包积液后注射奈达铂。结果所有患者均一次穿刺成功。16例患者中完全缓解13例(81.3%),部分缓解2例(12.5%),总有效率(完全缓解+部分缓解)为93.8%,胸闷、呼吸困难等心包填塞症状缓解。结论以中心静脉导管留置心包腔内引流心包积液并注射奈达铂,可迅速消除心包填塞症状,疗效明显,不良反应较轻,患者易于耐受,无心跳骤停及心律失常发生,无管腔堵塞、感染及缩窄性心包炎等并发症发生。
Objective To investigate the effects of drainage with central venous catheter and intracavitary administration of Nedaplatin in the treatment of malignant pericardia1 cavity effusion. Methods 16 cases with malignant pericardial effusion re- ceived central venous catheter drainage and injection Nedaplatin by ultrasound-guided pericardiocentesis. Results All cases re- ceived central venous catheter successfully with only 1 puncture. The symptoms such as chest tightness and shortness of breath were alleviated. The effective rate was 93.75% （ 15 out of 16 patients） for all the 16 patients with the malignant pericardial effu- sion. Conclusion The intrapericardial intubation and injection of Nedaplatin for treatment of malignant pericardial effusion has good therapeutic efficacy and can quickly relieve the symptoms of pericardial tamponade. There is no heart attack,cardiac arrhyth- mia,lumen blocked or infection and constrictive Dericarditis.
出处
《实用癌症杂志》
2013年第2期183-185,共3页
The Practical Journal of Cancer
关键词
奈达铂
恶性心包积液
Nedaplatin
Malignant pericardial effusion
