摘要
目的 :观察胸腺细胞腹腔注射佐治29例营养不良呼吸道感染患儿的临床效果及免疫功能。方法 :血清免疫球蛋白、SIL -2R、IL -2活性以及T淋巴细胞亚群分别采用快速免疫消浊比浊法 ,A PAAP、MTT以及ELISA法测定。结果 :与对照组比较 ,治疗前IL -2活性 ,CD3、CD4、和CD4/CD8 均明显降低(P<0.01) ,而SIL -2R则明显升高(P<0.01) ;治疗后 ,除SIL -2R明显降低(P<0.01)外 ,其余免疫学指标均明显升高(P<0.01) ,且临床治愈率82.76%明显高于对照组。结论
Objective:To observe the clinical effect as well as immune function when 29 cases of children with malnutrition concurrent with recurrent respiratory infection were treated adjuvantly by thymus cell transplantation.Methods:The levels of Ig,sIL-2R and IL-2 active and T lymphocyte subsets were respectively tested by the rapid turbidity method,ELISA,MTT and APAAP.Results:Before the treatment,IL-2 active,CD3,CD4 and CD4/CD8 were prominently low in the studied cases comparison with control group(P<0.01),however,the sIL-2R was higher(P<0.01).After the treatment,all the above indexes went up remarkably(P<0.01),except the level of sIL-2R down remarkably(P<0.01).The clinical cure rate(82.76%)is higher than that of control group.Conclusion:Thymus cells transplantation is beneficial to the recovery of patients with the disease.
出处
《大理医学院学报》
2000年第3期15-16,共2页
Journal of Dali Medical College
关键词
胸腺细胞
营养不良
呼吸道感染
婴幼儿
治疗
Thymus cells transplantation
Malnutrition
Recurrent respiratory infection
