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硝酸甘油治疗126例急性心肌梗死的临床体会 被引量:6

The clinical experience of nitroglycerin in the treatment of 126 patients with acute myocardial infarction
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摘要 目的探讨硝酸甘油在治疗急性心肌梗死时的临床疗效,总结其护理经验。方法将我院心内科收治的急性心肌梗死患者随机分为观察组和对照组,各126例,对照组给予镇静、止痛、吸氧等常规方案治疗,观察组在对照组治疗基础上加用硝酸甘油治疗,观察两组患者的总有效率、疼痛缓解时间、血压下降、心率增加、ST段下降率、心律失常率;总结护理措施。结果观察组患者治疗显效率为61.11%,总有效率为95.24%;明显高于对照组的49.21%与88.10%,差异有统计学意义(P<0.05);观察组疼痛缓解时间为(29.42±7.95)min,血压下降(2.35±0.71)kPa,心率增加(28.42±6.35)次/min,ST段下降率为65.08%,心律失常率为4.76%;明显高于对照组的(117.42±52.68)min、(1.32±0.58)kPa、(13.52±5.18)次/min和29.37%,差异有统计学意义(P<0.05)。结论硝酸甘油静脉滴注治疗急性心肌梗死临床疗效较好;详尽细致的护理工作有助于患者并发症及药物不良反应的预防,亦可为下一步治疗方案的制定提供可靠的参考。 Objective To investigate the clinical efficacy and nursing experience of nitroglycerin in the treatment of acute myocardial infarction.Methods The patients with acute myocardial infarction in the the Department of Cardiology in our hospital treatment were randomly divided into the observation group and the control group with 126 patients in each group.The patients in the control group were given sedative,analgesic,oxygen and other conventional treatment,while the patients in the observation group were treated with nitroglycerin treatment based on the control group,the total efficiency,pain relief,decreased blood pressure,increased heart rate,ST rate of decline,the arrhythmia rate;nursing measures of both groups were compared.Results The total effective rate in the observation group was 95.24%;significantly higher than that of control group(88.10%),the difference was statistically significant(P〈0.05);the pain relief time in the observation group was(29.42± 7.95) min,decreased blood pressure(2.35 ±0.71) kPa,heart rate increased(28.42 ±6.35) per min,ST segment descent rate was 65.08%,the arrhythmia rate was 4.76%;they were was higher than that in control group with(117.42 ±52.68) min,(1.32 ±0.58) kPa,(13.52 ±5.18) per min,and 29.37%,respectively,the difference was statistically significant(P〈0.05).Conclusion The clinical curative effect of intravenous infusion of nitroglycerin in patients with acute myocardial infarction is better;the nursing can contribute to the prevention of complications and adverse drug reactions,and also can provide reliable reference for the next treatment program.
作者 韩朝煜
出处 《四川医学》 CAS 2013年第2期326-328,共3页 Sichuan Medical Journal
关键词 硝酸甘油 急性心肌梗死 临床疗效 护理 nitroglycerin acute myocardial infarction clinical efficacy nursing care
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