摘要
骨质疏松症(OP)已经成为全球关注的社会健康问题,骨质疏松性髋部骨折是其最严重的并发症之一。人工关节置换术是治疗该并发症最有效的方法之一,它可以显著地提高患者的生存质量。目前全球每年有超过100万套的关节假体被植入,但是该手术后10年时因无菌性松动导致的关节失效翻修累积超过12%。但OP对人工关节置换术的远期无菌性松动是否有影响,如何影响,目前尚不清楚。我们拟从手术方式的选择、人工关节远期无菌性松动的机制和抗OP药物的作用来探讨OP对人工关节置换术后远期无菌性松动的影响。
Around the world, osteoporosis has gradually become a serious social and health issues. Osteoporotie hip fracture is the most severe complication. Arthroplasty is one of the most effective way to treat this complication which can significantly improve patients＇ life quality. Approximately one million joint arthroplasties are performed annually worldwide, but periprosthetic osteolysis and subsequent aseptic joint loosening happen in approximately 12% of patients within 10 years of the initial surgery. However, it is still unclear whether osteoporosis affects aseptic joint loosening. In this article, we review the choice of surgical method, mechanism of the aseptic joint loosening and anti-osteoprostic drug used in this filed.
出处
《中华关节外科杂志（电子版）》
CAS
2013年第1期89-93,共5页
Chinese Journal of Joint Surgery(Electronic Edition)
关键词
骨质疏松
人工关节
磨损颗粒
药物治疗
Osteoporosis
Joint prosthesis
Wear particle
Drug therapy
