摘要
目的:初步评价局部切除联合放射性粒子治疗早期舌癌(<2cm的T1期)的局部控制率及其并发症的相关结果。方法:对15例经病理组织学证实的高分化鳞状细胞癌(<2cm的早期舌癌)患者施行了局部非广泛性切除和肩胛舌骨肌以上的颈清扫术,以生物补片覆盖创面,然后放射性粒子定向植入治疗。结果:经12～25个月的随访,有效控制率达93.33%(14/15),仅1例术后9个月出现局部复发后再次手术行广泛性切除。未见明显放射治疗后出现的口干、骨坏死和张口受限等并发症。本组出现的疼痛、充血性糜烂和水肿等并发症随剂量的衰减而逐渐缓解。结论:对<2cm的早期舌癌应用局部切除联合放射性粒子植入治疗是一种安全可靠,有着良好疗效并有应用前景的方法。
Objective.. To evaluate the relative incidence of local control and complications in patients with early tongue cancer （〈2cm T1 period） who underwent local resection plus radioactive seeds implantation. Method： Fifteen patients with high differentiated squamous cell carcinoma （ 〈2cm of early tongue cancer） reoperatively confirmed by pathological examination were treated with local non-wide resection plus omohyoid muscle above the neck dissections,hiofilms covering, and radioactive seed implanting. Result： During the 12 to 25 months of follow-up periods, the effective rate was 93.33% （14/15）, only 1 patient lined wide resection for local recurrence within 9 month after surgery. No obvious dry mouth, bone necrosis , limited mouth opening, and other complications after radiation therapy. Pain, erosion and edema of congestive were eased with attenuation of doses. Conclusion： The treatment for early tongue cancer （〈2cm） using the method of local resection plus radioactive seeds implantation is safe, reliable, effective, and promising clinic application.
出处
《口腔医学研究》
CAS
CSCD
2013年第3期277-280,共4页
Journal of Oral Science Research
