摘要
目的：比较西咪替丁与奥美拉唑治疗胃溃疡的临床疗效。方法：将我院2010年1月~2011年12月间收治的86例胃溃疡患者随机分为西咪替丁治疗组（A组）和奥美拉唑治疗组（B组）,每组各43例,比较两组患者的临床疗效。结果：奥美拉唑治疗组患者的治疗总有效率为93.0%,显著高于西咪替丁治疗组的74.4%,组间差异有统计学意义（P〈0.05）。停药4周后,奥美拉唑组溃疡复发率为4.7%,低于西咪替丁组的18.6%,组间差异有统计学意义（P〈0.05）。两组患者在治疗过程中均未发生严重的不良反应。结论：奥美拉唑在治疗胃溃疡和预防溃疡复发方面较西咪替丁更为有效,且无严重不良反应,值得临床进一步推广使用。
Objective：Comparison of cimetidine and omeprazole in treatment of gastric ulcer.Methods： The hospital treated 86 cases of gastric ulcer patients were randomly divided into treatment group（group A） of cimetidine and omeprazole group（group B） in 43 cases,comparing the two groups of patients with clinical efficacy.Results： The patients in the A group total effective rate was 93%,significantly higher than that of B74.4%（P0.05）,significant difference.4 weeks later,group A ulcer recurrence rate of 4.7%,lower than the18.6% in B group,had significant difference（P0.05）.Two groups were no adverse reaction.Conclusion： Omeprazole in treatment of gastric ulcer and preventing recurrence of peptic ulcer with cimetidine is more effective,and no serious adverse reaction,is worth popularizing.
出处
《中国医药导刊》
2013年第2期301-301,317,共2页
Chinese Journal of Medicinal Guide
关键词
胃溃疡
西咪替丁
奥美拉唑
临床疗效
Gastric ulcer
Cimetidine
Omeprazole
Clinical curative effect
