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严重脓毒症中医证型与病情严重度及预后相关性的临床研究 被引量:21

Study on the association of TCM syndrome type with severity / prognosis in severe sepsis patients
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摘要 目的探讨严重脓毒症中医证型与病情严重度及预后的相关性。方法对严重脓毒症患者进行中医辨证,记录患者一般情况、APACHE-II分值及转归,对其进行统计分析。结果在105例严重脓毒症患者中,原发病以呼吸道感染最多(77例,73.3%)。发生率较高的证型是热证(105例,100%)、腑气不通证(94例,89.5%)。多数患者非单一证型(101例,96.2%)。合并四种证型组的入院APACHE-II评分最高(27.75±7.436分,P=0.018)。合并四种证型组死亡率最高(21例,65.6%,P=0.012)。结论在严重脓毒症患者中,呼吸道感染最多见的,热证及腑气不通证是最常见的中医证型,合并的证型数越多,其入院时APACHE-II评分越高,病死率也越高。 Objective To observe the relationship between Traditional Chinese Medicine syndrome pattern and severity / prognosis in se- vere sepsis patients . Methods To perform the identification of Traditional Chinese Medical syndrome pattern. Record the clinical indexes nee- ded. laboratory data, APACHE - II score and 28 days mortality are selected as the main observing indexes. The results were analyzed statistically. Results In severe sepsis, the most common site of infection are respiratory tract (77 cases, 73.3 % ) . All sepsis patients with heat, with stop- page offu-qi are 94 cases (89.5%) . Patients with several syndromes are 101 cases (3.81%). (First day) The top average APACHE -II score is the four syndrome types group is 27.75 + 7. 436, P = 0.018 . The four syndrome types group had the highest mortality it is 21 (65, 6% ), P = 0. 012. Conchmiou In severe sepsis, the most common site of infection are respiratory tract. Heat and stoppage of fu - qi is the most com- mon TCM syndrome. The more kinds of TCM syndrome, the more APACHE - II scores and mortality.
出处 《临床和实验医学杂志》 2013年第5期377-380,共4页 Journal of Clinical and Experimental Medicine
基金 首都医学发展科研基金支持项目SF-2009-I-11
关键词 严重脓毒症 中医证型 APACHE—II 病死率 Severe sepsis Syndrome ofTCM APACHE-II Mortality
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