摘要
【目的】探讨急性胰腺炎患者血清白细胞介素-22（IL-22）的水平及意义。【方法】采用酶联免疫吸附法检测66例急性胰腺炎患者和60例同期住院的非胰腺疾病患者血清IL-22的水平。【结果】急性胰腺炎患者血清IL-22水平显著高于对照组，与患者的年龄及性别无关，重症胰腺炎患者血清IL-22水平高于轻度胰腺炎患者。【结论】急性胰腺炎患者血清IL-22的水平较对照组增加，且与病情严重程度相关，可作为急性胰腺炎诊断和病情评估的潜在生物学靶点。
[Objective] To explore the level and significance of serum interleukin-22（IL-22） in patients with acute pancreatitis. [Methods]Serum IL-22 of 56 patients with acute pancreatitis and 60 patients without pancreatic disease was detected by ELISA. [Results] Serum IL-22 in patients with acute pancreatitis was remarkably higher than that in control group. The level of 1L-22 was not related with age and gender. The level of serum IL-22 in patients with severe acute pancreatitis was higher than that in patients with mild acute pancreatitis. [Conclusion] Compared with control group, ser- um IL-22 in patients with acute pancreatitis increases, and is correlated with the severity of the patients＂ condition. IL-22 can be regarded to be a potential biomarker in the diagnosis and condition assessment of acute pancreatitis.
出处
《医学临床研究》
CAS
2013年第2期308-309,312,共3页
Journal of Clinical Research
