摘要
目的:总结和分析近10年国内医学期刊公开发表的中药内服治疗膝骨关节炎的文献中特殊中药应用现状。方法:通过统一检索式,委托专业文献查新人员检索万方、维普、CNKI三大数据库,再通过纳入标准、排除标准、资料提取与文献质量评价3个环节对检索结果进行分析。并对药物分类、特殊用药前20位药物出现频次及出现百分率进行排序。结果:最终有效文献为491篇,其中出现特殊用药的文献有209篇。中药内服治疗膝骨关节炎特殊用药前20位的药物排序依次为川乌、细辛、蜈蚣、附子、土鳖虫、草乌、全蝎、半夏、胆南星、马钱子、桃仁、红花、乌梢蛇、水蛭、血竭、三七、延胡索、路路通、穿山甲、白花蛇;药物功效分类依次为祛风寒湿药、活血止痛药、活血调经药、活血疗伤药、破血消癥药、息风止痉药、发散风寒药、温里药、温化寒痰药、化瘀止血药。结论:风、寒、湿三邪可能为膝骨关节炎的主要致病外因;膝骨关节炎风寒湿痹证出现的频率可能要比热痹证出现的频率高。
To summarize and analyze the application status of the special traditional Chinese medicine in the treat- ment of knee osteoarthritis cases which collected from the domestic medical journals in recent 10 years. Methods：The clini- cal materials were electronically searched from Wanfang, Weipu and CNKI databases by professional novelty--retrieving personnel. And then it was analyzed according to inclusion criteria, exclusion criterion and the quality of literatures. Drug classification and the top 20 special drugs was sorted according to its occurrence frequency or percentage. Results： Special medication appeared in 209 of the final 491 effective articles. The top 20 special Chinese medicine treating knee osteoarthritis are monkshood, asarum, centipede, aconite, ground beetle, radix aconiti kusnezoffii, scorpion, pinellia, arisaema cum bile, semen strychni, semen persicae, safflower, zaocys dhumnades, leech, dragon blood, panax notoginseng, corydalis, Lulutong, pangolin and herba hedyotidis diffusae. These Chinese medicines were classified by medical effect as follows： drugs for eliminating wind-cold-dampness, drugs for activating blood analgesia, drugs for regulating menstruation , drugs for healing by activating blood, drugs for removing blood stasis , dispelling wind-cold medicine, drugs for interior-warming , drugs for blowing out wind and antispasmodic , drugs for warming and melting cold sputum and drugs for hemostasia by removing blood stasis. Conclusion：Wind, coldness and dampness are probably the major external etiologies of knee osteoar- thritis. The frequency of knee arthralgia syndrome caused by wind cold damp impediment may be more than that of heat type arthralgia.
出处
《中国中医骨伤科杂志》
CAS
2013年第3期36-38,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
中药内服
膝骨关节炎
文献
特殊中药
应用现状
Chinese herbs
knee osteoarthritis
literature
special traditional Chinese medicine
application status
