摘要
合成 7,8 二甲基二联吡啶并 (3 ,2 ,a:2′ ,3′ ,c)吩嗪 ,简称dppx ,并合成了Ru(bpy) 2 dppx2 +混配物 ,研究了混配物与DNA作用的紫外 可见光谱与荧光光谱。在pH 9 5时DNA能使混配物的紫外可见光谱发生明显的减色效应 ,荧光光谱在 5 99nm处 (λex=4 71nm)产生新的荧光峰 ,探讨了反应的机理。
New Complexes Ru(bpy) 2dppx 2+ were synthesized.The binding of Ru(bpy) 2dppx 2+ to calf thymus DNA has been investigated by using electronic absorption and fluorescence spectra.The intercalation mode was proved to exist.The DNA leads to a dramatic enhancement of the photoluminescence of the drug at 599 nm ( λ ex =471 nm) and absorption hypochromic effect and red shift.It was obvious that Ruthenium complexes may be used at a good DNA probe.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2000年第4期575-576,共2页
Spectroscopy and Spectral Analysis
关键词
钌配合物
荧光光谱
紫外-可见光谱
DNA
结构
Ruthenium complexes, Calf thymus DNA, Fluorescence and absorption spectra
